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Page 1
BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.
Copsel SN, Lightbourn CO, Barreras H, Lohse I, Wolf D, Bader CS, Manov J, Kale BJ, Shah D, Brothers SP, Perez VL, Komanduri KV, Wahlestedt C, Levy RB. Copsel SN, et al. Among authors: bader cs. Front Immunol. 2019 Jan 24;9:3104. doi: 10.3389/fimmu.2018.03104. eCollection 2018. Front Immunol. 2019. PMID: 30733722 Free PMC article.
Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation.
Wolf D, Barreras H, Bader CS, Copsel S, Lightbourn CO, Pfeiffer BJ, Altman NH, Podack ER, Komanduri KV, Levy RB. Wolf D, et al. Among authors: bader cs. Biol Blood Marrow Transplant. 2017 May;23(5):757-766. doi: 10.1016/j.bbmt.2017.02.013. Epub 2017 Feb 20. Biol Blood Marrow Transplant. 2017. PMID: 28219835 Free PMC article.
Very Low Numbers of CD4+ FoxP3+ Tregs Expanded in Donors via TL1A-Ig and Low-Dose IL-2 Exhibit a Distinct Activation/Functional Profile and Suppress GVHD in a Preclinical Model.
Copsel S, Wolf D, Kale B, Barreras H, Lightbourn CO, Bader CS, Alperstein W, Altman NH, Komanduri KV, Levy RB. Copsel S, et al. Among authors: bader cs. Biol Blood Marrow Transplant. 2018 Sep;24(9):1788-1794. doi: 10.1016/j.bbmt.2018.04.026. Epub 2018 May 8. Biol Blood Marrow Transplant. 2018. PMID: 29751114 Free PMC article.
Immunoregulatory effects of RGMb in gut inflammation.
Pérez-Cruz M, Iliopoulou BP, Hsu K, Wu HH, Erkers T, Swaminathan K, Tang SW, Bader CS, Kambham N, Xie B, Dekruyff RH, Freeman GJ, Meyer E. Pérez-Cruz M, et al. Among authors: bader cs. Front Immunol. 2022 Nov 7;13:960329. doi: 10.3389/fimmu.2022.960329. eCollection 2022. Front Immunol. 2022. PMID: 36420263 Free PMC article.
Regulatory T Cell Amelioration of Graft-versus-Host Disease following Allogeneic/Xenogeneic Hematopoietic Stem Cell Transplantation Using Mobilized Mouse and Human Peripheral Blood Donors.
Barreras H, Copsel SN, Bader CS, Ding Y, Wolf D, Cash C, Stacey CJ, Benjamin C, Seavey MM, Wolf J, Jasuja RR, Pfeiffer B, Hill GR, Komanduri KV, Jurecic R, Malek TR, Levy RB. Barreras H, et al. Among authors: bader cs. Transplant Cell Ther. 2023 May;29(5):341.e1-341.e9. doi: 10.1016/j.jtct.2023.02.015. Epub 2023 Feb 18. Transplant Cell Ther. 2023. PMID: 36804930 Free PMC article.
Minnelide suppresses GVHD and enhances survival while maintaining GVT responses.
Copsel SN, Garrido VT, Barreras H, Bader CS, Pfeiffer B, Mateo-Victoriano B, Wolf D, Gallardo M, Paczesny S, Komanduri KV, Benjamin CL, Villarino AV, Saluja AK, Levy RB. Copsel SN, et al. Among authors: bader cs. JCI Insight. 2024 Apr 11;9(9):e165936. doi: 10.1172/jci.insight.165936. JCI Insight. 2024. PMID: 38602775 Free PMC article.
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