Spiegelman NA - Search Results

1

A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation.

Spiegelman NA, Hong JY, Hu J, Jing H, Wang M, Price IR, Cao J, Yang M, Zhang X, Lin H. Spiegelman NA, et al. ChemMedChem. 2019 Apr 3;14(7):744-748. doi: 10.1002/cmdc.201800715. Epub 2019 Feb 25. ChemMedChem. 2019. PMID: 30734528 Free PMC article.

2

SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.

Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H. Zhang X, et al. Among authors: spiegelman na. Elife. 2017 Apr 13;6:e25158. doi: 10.7554/eLife.25158. Elife. 2017. PMID: 28406396 Free PMC article.

3

SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a.

Jing H, Zhang X, Wisner SA, Chen X, Spiegelman NA, Linder ME, Lin H. Jing H, et al. Among authors: spiegelman na. Elife. 2017 Dec 14;6:e32436. doi: 10.7554/eLife.32436. Elife. 2017. PMID: 29239724 Free PMC article.

4

Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities.

Spiegelman NA, Price IR, Jing H, Wang M, Yang M, Cao J, Hong JY, Zhang X, Aramsangtienchai P, Sadhukhan S, Lin H. Spiegelman NA, et al. ChemMedChem. 2018 Sep 19;13(18):1890-1894. doi: 10.1002/cmdc.201800391. Epub 2018 Aug 13. ChemMedChem. 2018. PMID: 30058233 Free PMC article.

5

SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration.

Spiegelman NA, Zhang X, Jing H, Cao J, Kotliar IB, Aramsangtienchai P, Wang M, Tong Z, Rosch KM, Lin H. Spiegelman NA, et al. ACS Chem Biol. 2019 Sep 20;14(9):2014-2023. doi: 10.1021/acschembio.9b00492. Epub 2019 Sep 3. ACS Chem Biol. 2019. PMID: 31433161 Free PMC article.

6

Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation.

Wang M, Zhang Y, Komaniecki GP, Lu X, Cao J, Zhang M, Yu T, Hou D, Spiegelman NA, Yang M, Price IR, Lin H. Wang M, et al. Among authors: spiegelman na. Nat Commun. 2022 Aug 2;13(1):4494. doi: 10.1038/s41467-022-32227-x. Nat Commun. 2022. PMID: 35918380 Free PMC article.

7

HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine.

Aramsangtienchai P, Spiegelman NA, He B, Miller SP, Dai L, Zhao Y, Lin H. Aramsangtienchai P, et al. Among authors: spiegelman na. ACS Chem Biol. 2016 Oct 21;11(10):2685-2692. doi: 10.1021/acschembio.6b00396. Epub 2016 Aug 5. ACS Chem Biol. 2016. PMID: 27459069 Free PMC article.

8

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2.

Cao J, Sun L, Aramsangtienchai P, Spiegelman NA, Zhang X, Huang W, Seto E, Lin H. Cao J, et al. Among authors: spiegelman na. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5487-5492. doi: 10.1073/pnas.1815365116. Epub 2019 Feb 28. Proc Natl Acad Sci U S A. 2019. PMID: 30819897 Free PMC article.

9

Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling.

Zhang S, Spiegelman NA, Lin H. Zhang S, et al. Among authors: spiegelman na. Methods Mol Biol. 2019;2009:137-147. doi: 10.1007/978-1-4939-9532-5_11. Methods Mol Biol. 2019. PMID: 31152401 Free PMC article.

10

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

Zhang X, Khan S, Jiang H, Antonyak MA, Chen X, Spiegelman NA, Shrimp JH, Cerione RA, Lin H. Zhang X, et al. Among authors: spiegelman na. Nat Chem Biol. 2016 Aug;12(8):614-20. doi: 10.1038/nchembio.2106. Epub 2016 Jun 20. Nat Chem Biol. 2016. PMID: 27322069 Free PMC article.

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