Leight JL - Search Results

1

Measuring Global Cellular Matrix Metalloproteinase and Metabolic Activity in 3D Hydrogels.

Fakhouri AS, Leight JL. Fakhouri AS, et al. Among authors: leight jl. J Vis Exp. 2019 Jan 22;(143). doi: 10.3791/59123. J Vis Exp. 2019. PMID: 30735180

2

Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition.

Leight JL, Tokuda EY, Jones CE, Lin AJ, Anseth KS. Leight JL, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5366-71. doi: 10.1073/pnas.1505662112. Epub 2015 Apr 13. Proc Natl Acad Sci U S A. 2015. PMID: 25870264 Free PMC article.

3

Detection of Protease Activity by Fluorescent Peptide Zymography.

Deshmukh AA, Weist JL, Leight JL. Deshmukh AA, et al. Among authors: leight jl. J Vis Exp. 2019 Jan 20;(143). doi: 10.3791/58938. J Vis Exp. 2019. PMID: 30735202

4

High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity.

Fakhouri AS, Weist JL, Tomusko AR, Leight JL. Fakhouri AS, et al. Among authors: leight jl. Assay Drug Dev Technol. 2019 Apr;17(3):100-115. doi: 10.1089/adt.2018.877. Assay Drug Dev Technol. 2019. PMID: 30958702

5

A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity.

Dedhia PH, Sivakumar H, Rodriguez MA, Nairon KG, Zent JM, Zheng X, Jones K, Popova LV, Leight JL, Skardal A. Dedhia PH, et al. Among authors: leight jl. Sci Rep. 2023 Sep 19;13(1):15508. doi: 10.1038/s41598-023-42659-0. Sci Rep. 2023. PMID: 37726363 Free PMC article.

6

Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate.

Leight JL, Alge DL, Maier AJ, Anseth KS. Leight JL, et al. Biomaterials. 2013 Oct;34(30):7344-52. doi: 10.1016/j.biomaterials.2013.06.023. Epub 2013 Jul 2. Biomaterials. 2013. PMID: 23830581 Free PMC article.

7

Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness.

Tokuda EY, Leight JL, Anseth KS. Tokuda EY, et al. Among authors: leight jl. Biomaterials. 2014 May;35(14):4310-8. doi: 10.1016/j.biomaterials.2014.01.063. Epub 2014 Feb 22. Biomaterials. 2014. PMID: 24565518 Free PMC article.

8

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.

Jones CE, Hammer AM, Cho Y, Sizemore GM, Cukierman E, Yee LD, Ghadiali SN, Ostrowski MC, Leight JL. Jones CE, et al. Among authors: leight jl. Neoplasia. 2019 Jan;21(1):132-145. doi: 10.1016/j.neo.2018.10.010. Epub 2018 Dec 12. Neoplasia. 2019. PMID: 30550871 Free PMC article.

9

Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation.

Campbell WA 4th, Deshmukh A, Blum S, Todd L, Mendonca N, Weist J, Zent J, Hoang TV, Blackshaw S, Leight J, Fischer AJ. Campbell WA 4th, et al. Exp Neurol. 2019 Oct;320:112984. doi: 10.1016/j.expneurol.2019.112984. Epub 2019 Jun 25. Exp Neurol. 2019. PMID: 31251936 Free PMC article.

10

Click chemistry functionalization of self-assembling peptide hydrogels.

Sharick JT, Atieh AJ, Gooch KJ, Leight JL. Sharick JT, et al. Among authors: leight jl. J Biomed Mater Res A. 2023 Mar;111(3):389-403. doi: 10.1002/jbm.a.37460. Epub 2022 Oct 10. J Biomed Mater Res A. 2023. PMID: 36210776 Free PMC article.

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