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PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. Nawrotek A, et al. Among authors: st onge rp. Nat Chem Biol. 2019 Apr;15(4):358-366. doi: 10.1038/s41589-019-0228-3. Epub 2019 Feb 11. Nat Chem Biol. 2019. PMID: 30742123
PITPs as targets for selectively interfering with phosphoinositide signaling in cells.
Nile AH, Tripathi A, Yuan P, Mousley CJ, Suresh S, Wallace IM, Shah SD, Pohlhaus DT, Temple B, Nislow C, Giaever G, Tropsha A, Davis RW, St Onge RP, Bankaitis VA. Nile AH, et al. Among authors: st onge rp. Nat Chem Biol. 2014 Jan;10(1):76-84. doi: 10.1038/nchembio.1389. Epub 2013 Nov 24. Nat Chem Biol. 2014. PMID: 24292071 Free PMC article.
An integrated platform of genomic assays reveals small-molecule bioactivities.
Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C. Hoon S, et al. Among authors: st onge rp. Nat Chem Biol. 2008 Aug;4(8):498-506. doi: 10.1038/nchembio.100. Epub 2008 Jul 11. Nat Chem Biol. 2008. PMID: 18622389
Yeast chemical genomics and drug discovery: an update.
Hoon S, St Onge RP, Giaever G, Nislow C. Hoon S, et al. Among authors: st onge rp. Trends Pharmacol Sci. 2008 Oct;29(10):499-504. doi: 10.1016/j.tips.2008.07.006. Epub 2008 Aug 26. Trends Pharmacol Sci. 2008. PMID: 18755517 Review.
47 results