Zeghouf M - Search Results

1

PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.

Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. Nawrotek A, et al. Among authors: zeghouf m. Nat Chem Biol. 2019 Apr;15(4):358-366. doi: 10.1038/s41589-019-0228-3. Epub 2019 Feb 11. Nat Chem Biol. 2019. PMID: 30742123

2

Arf, Sec7 and Brefeldin A: a model towards the therapeutic inhibition of guanine nucleotide-exchange factors.

Zeghouf M, Guibert B, Zeeh JC, Cherfils J. Zeghouf M, et al. Biochem Soc Trans. 2005 Dec;33(Pt 6):1265-8. doi: 10.1042/BST0331265. Biochem Soc Trans. 2005. PMID: 16246094 Review.

3

Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains.

Zeeh JC, Zeghouf M, Grauffel C, Guibert B, Martin E, Dejaegere A, Cherfils J. Zeeh JC, et al. Among authors: zeghouf m. J Biol Chem. 2006 Apr 28;281(17):11805-14. doi: 10.1074/jbc.M600149200. Epub 2006 Feb 16. J Biol Chem. 2006. PMID: 16484231 Free article.

4

Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes.

Viaud J, Zeghouf M, Barelli H, Zeeh JC, Padilla A, Guibert B, Chardin P, Royer CA, Cherfils J, Chavanieu A. Viaud J, et al. Among authors: zeghouf m. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10370-5. doi: 10.1073/pnas.0700773104. Epub 2007 Jun 11. Proc Natl Acad Sci U S A. 2007. PMID: 17563369 Free PMC article.

5

In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors.

Zeeh JC, Antonny B, Cherfils J, Zeghouf M. Zeeh JC, et al. Among authors: zeghouf m. Methods Enzymol. 2008;438:41-56. doi: 10.1016/S0076-6879(07)38004-X. Methods Enzymol. 2008. PMID: 18413240

6

An Arf1 GTPase mutant with different responses to GEF inhibitors.

Flisiak S, Zeeh JC, Guibert B, Cherfils J, Zeghouf M. Flisiak S, et al. Among authors: zeghouf m. Biochem Biophys Res Commun. 2008 Dec 5;377(1):156-60. doi: 10.1016/j.bbrc.2008.09.107. Epub 2008 Oct 1. Biochem Biophys Res Commun. 2008. PMID: 18834864

7

Aptamer-derived peptides as potent inhibitors of the oncogenic RhoGEF Tgat.

Bouquier N, Fromont S, Zeeh JC, Auziol C, Larrousse P, Robert B, Zeghouf M, Cherfils J, Debant A, Schmidt S. Bouquier N, et al. Among authors: zeghouf m. Chem Biol. 2009 Apr 24;16(4):391-400. doi: 10.1016/j.chembiol.2009.02.006. Chem Biol. 2009. PMID: 19389625 Free article.

8

SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6.

Biou V, Aizel K, Roblin P, Thureau A, Jacquet E, Hansson S, Guibert B, Guittet E, van Heijenoort C, Zeghouf M, Perez J, Cherfils J. Biou V, et al. Among authors: zeghouf m. J Mol Biol. 2010 Oct 1;402(4):696-707. doi: 10.1016/j.jmb.2010.08.002. Epub 2010 Aug 13. J Mol Biol. 2010. PMID: 20709080

9

LG186: An inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells.

Boal F, Guetzoyan L, Sessions RB, Zeghouf M, Spooner RA, Lord JM, Cherfils J, Clarkson GJ, Roberts LM, Stephens DJ. Boal F, et al. Among authors: zeghouf m. Traffic. 2010 Dec;11(12):1537-51. doi: 10.1111/j.1600-0854.2010.01122.x. Epub 2010 Oct 15. Traffic. 2010. PMID: 20854417 Free article.

10

Chronicles of the GTPase switch.

Cherfils J, Zeghouf M. Cherfils J, et al. Among authors: zeghouf m. Nat Chem Biol. 2011 Jul 18;7(8):493-5. doi: 10.1038/nchembio.608. Nat Chem Biol. 2011. PMID: 21769091 No abstract available.

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