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Alginate-microencapsulation of human stem cell-derived β cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression.
Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC. Alagpulinsa DA, et al. Among authors: melton da. Am J Transplant. 2019 Jul;19(7):1930-1940. doi: 10.1111/ajt.15308. Epub 2019 Mar 25. Am J Transplant. 2019. PMID: 30748094 Free article.
Generation of pluripotent stem cells from patients with type 1 diabetes.
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, Leibel RL, Melton DA. Maehr R, et al. Among authors: melton da. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15768-73. doi: 10.1073/pnas.0906894106. Epub 2009 Aug 31. Proc Natl Acad Sci U S A. 2009. PMID: 19720998 Free PMC article.
How to make beta cells?
Borowiak M, Melton DA. Borowiak M, et al. Among authors: melton da. Curr Opin Cell Biol. 2009 Dec;21(6):727-32. doi: 10.1016/j.ceb.2009.08.006. Epub 2009 Sep 24. Curr Opin Cell Biol. 2009. PMID: 19781928 Free PMC article. Review.
How to make a functional β-cell.
Pagliuca FW, Melton DA. Pagliuca FW, et al. Among authors: melton da. Development. 2013 Jun;140(12):2472-83. doi: 10.1242/dev.093187. Development. 2013. PMID: 23715541 Free PMC article. Review.
Differentiated human stem cells resemble fetal, not adult, β cells.
Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA. Hrvatin S, et al. Among authors: melton da. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3038-43. doi: 10.1073/pnas.1400709111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516164 Free PMC article.
Generation of functional human pancreatic β cells in vitro.
Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. Pagliuca FW, et al. Among authors: melton da. Cell. 2014 Oct 9;159(2):428-39. doi: 10.1016/j.cell.2014.09.040. Cell. 2014. PMID: 25303535 Free PMC article.
245 results