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Evaluation of the efficacy, safety and tolerability of orally administered BI 409306, a novel phosphodiesterase type 9 inhibitor, in two randomised controlled phase II studies in patients with prodromal and mild Alzheimer's disease.
Frölich L, Wunderlich G, Thamer C, Roehrle M, Garcia M Jr, Dubois B. Frölich L, et al. Among authors: roehrle m. Alzheimers Res Ther. 2019 Feb 12;11(1):18. doi: 10.1186/s13195-019-0467-2. Alzheimers Res Ther. 2019. PMID: 30755255 Free PMC article. Clinical Trial.
HCVerso1 and 2: faldaprevir with deleobuvir (BI 207127) and ribavirin for treatment-naïve patients with chronic hepatitis C virus genotype-1b infection.
Sarrazin C, Castelli F, Andreone P, Buti M, Colombo M, Pol S, Calinas F, Puoti M, Olveira A, Shiffman M, Stern JO, Kukolj G, Roehrle M, Aslanyan S, Deng Q, Vinisko R, Mensa FJ, Nelson DR. Sarrazin C, et al. Among authors: roehrle m. Clin Exp Gastroenterol. 2016 Nov 24;9:351-363. doi: 10.2147/CEG.S111116. eCollection 2016. Clin Exp Gastroenterol. 2016. PMID: 27920566 Free PMC article.
Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL4815 after intravenous infusion and oral administration of its prodrug, BAL8557, in healthy volunteers.
Schmitt-Hoffmann A, Roos B, Maares J, Heep M, Spickerman J, Weidekamm E, Brown T, Roehrle M. Schmitt-Hoffmann A, et al. Among authors: roehrle m. Antimicrob Agents Chemother. 2006 Jan;50(1):286-93. doi: 10.1128/AAC.50.1.286-293.2006. Antimicrob Agents Chemother. 2006. PMID: 16377699 Free PMC article. Clinical Trial.
Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL4815 after intravenous infusions (50, 100, and 200 milligrams) and oral administrations (100, 200, and 400 milligrams) of its prodrug, BAL8557, in healthy volunteers.
Schmitt-Hoffmann A, Roos B, Heep M, Schleimer M, Weidekamm E, Brown T, Roehrle M, Beglinger C. Schmitt-Hoffmann A, et al. Among authors: roehrle m. Antimicrob Agents Chemother. 2006 Jan;50(1):279-85. doi: 10.1128/AAC.50.1.279-285.2006. Antimicrob Agents Chemother. 2006. PMID: 16377698 Free PMC article. Clinical Trial.