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Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
Molkentine JM, Fujimoto TN, Horvath TD, Grossberg AJ, Garcia CJG, Deorukhkar A, de la Cruz Bonilla M, Lin D, Samuel ELG, Chan WK, Lorenzi PL, Piwnica-Worms H, Dantzer R, Tour JM, Mason KA, Taniguchi CM. Molkentine JM, et al. Among authors: lorenzi pl. Sci Rep. 2019 Feb 13;9(1):1949. doi: 10.1038/s41598-018-37147-9. Sci Rep. 2019. PMID: 30760738 Free PMC article.
Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer.
Horvath TD, Chan WK, Pontikos MA, Martin LA, Du D, Tan L, Konopleva M, Weinstein JN, Lorenzi PL. Horvath TD, et al. Among authors: lorenzi pl. Metabolites. 2019 Jan 9;9(1):10. doi: 10.3390/metabo9010010. Metabolites. 2019. PMID: 30634463 Free PMC article.
Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia.
Chan WK, Horvath TD, Tan L, Link T, Harutyunyan KG, Pontikos MA, Anishkin A, Du D, Martin LA, Yin E, Rempe SB, Sukharev S, Konopleva M, Weinstein JN, Lorenzi PL. Chan WK, et al. Among authors: lorenzi pl. Mol Cancer Ther. 2019 Sep;18(9):1587-1592. doi: 10.1158/1535-7163.MCT-18-1329. Epub 2019 Jun 17. Mol Cancer Ther. 2019. PMID: 31209181 Free PMC article.
Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer.
Cargill KR, Stewart CA, Park EM, Ramkumar K, Gay CM, Cardnell RJ, Wang Q, Diao L, Shen L, Fan YH, Chan WK, Lorenzi PL, Oliver TG, Wang J, Byers LA. Cargill KR, et al. Among authors: lorenzi pl. Cancer Metab. 2021 Sep 23;9(1):33. doi: 10.1186/s40170-021-00270-9. Cancer Metab. 2021. PMID: 34556188 Free PMC article.
Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring.
Colbert LE, El Alam MB, Wang R, Karpinets T, Lo D, Lynn EJ, Harris TA, Elnaggar JH, Yoshida-Court K, Tomasic K, Bronk JK, Sammouri J, Yanamandra AV, Olvera AV, Carlin LG, Sims T, Delgado Medrano AY, Napravnik TC, O'Hara M, Lin D, Abana CO, Li HX, Eifel PJ, Jhingran A, Joyner M, Lin L, Ramondetta LM, Futreal AM, Schmeler KM, Mathew G, Dorta-Estremera S, Zhang J, Wu X, Ajami NJ, Wong M, Taniguchi C, Petrosino JF, Sastry KJ, Okhuysen PC, Martinez SA, Tan L, Mahmud I, Lorenzi PL, Wargo JA, Klopp AH. Colbert LE, et al. Among authors: lorenzi pl. Cancer Cell. 2023 Nov 13;41(11):1945-1962.e11. doi: 10.1016/j.ccell.2023.09.012. Epub 2023 Oct 19. Cancer Cell. 2023. PMID: 37863066 Free PMC article.
126 results