Flecken T - Search Results

1

Mapping the Heterogeneity of Histone Modifications on Hepatitis B Virus DNA Using Liver Needle Biopsies Obtained from Chronically Infected Patients.

Flecken T, Meier MA, Skewes-Cox P, Barkan DT, Heim MH, Wieland SF, Holdorf MM. Flecken T, et al. J Virol. 2019 Apr 17;93(9):e02036-18. doi: 10.1128/JVI.02036-18. Print 2019 May 1. J Virol. 2019. PMID: 30787147 Free PMC article. Clinical Trial.

2

Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection.

Nitschke K, Flecken T, Schmidt J, Gostick E, Marget M, Neumann-Haefelin C, Blum HE, Price DA, Thimme R. Nitschke K, et al. Among authors: flecken t. J Virol. 2015 Jan;89(1):25-34. doi: 10.1128/JVI.02242-14. Epub 2014 Oct 15. J Virol. 2015. PMID: 25320295 Free PMC article.

3

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.

Flecken T, Schmidt N, Hild S, Gostick E, Drognitz O, Zeiser R, Schemmer P, Bruns H, Eiermann T, Price DA, Blum HE, Neumann-Haefelin C, Thimme R. Flecken T, et al. Hepatology. 2014 Apr;59(4):1415-26. doi: 10.1002/hep.26731. Epub 2014 Feb 20. Hepatology. 2014. PMID: 24002931 Free PMC article.

4

Suppressive effect of interleukin 10 on priming of naive hepatitis C virus-specific CD8+ T cells.

Niesen E, Schmidt J, Flecken T, Thimme R. Niesen E, et al. Among authors: flecken t. J Infect Dis. 2015 Mar 1;211(5):821-6. doi: 10.1093/infdis/jiu541. Epub 2014 Oct 29. J Infect Dis. 2015. PMID: 25355941

5

Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26).

Bengsch B, Seigel B, Flecken T, Wolanski J, Blum HE, Thimme R. Bengsch B, et al. Among authors: flecken t. J Immunol. 2012 Jun 1;188(11):5438-47. doi: 10.4049/jimmunol.1103801. Epub 2012 Apr 25. J Immunol. 2012. PMID: 22539793

6

Tumor-associated antigen specific CD8⁺ T cells in hepatocellular carcinoma - a promising target for immunotherapy.

Schmidt N, Flecken T, Thimme R. Schmidt N, et al. Among authors: flecken t. Oncoimmunology. 2014 Dec 13;3(9):e954919. doi: 10.4161/21624011.2014.954919. eCollection 2014 Oct. Oncoimmunology. 2014. PMID: 25941604 Free PMC article.

7

TGF-β downregulates KLRG1 expression in mouse and human CD8(+) T cells.

Schwartzkopff S, Woyciechowski S, Aichele U, Flecken T, Zhang N, Thimme R, Pircher H. Schwartzkopff S, et al. Among authors: flecken t. Eur J Immunol. 2015 Aug;45(8):2212-7. doi: 10.1002/eji.201545634. Epub 2015 Jun 15. Eur J Immunol. 2015. PMID: 26014037 Free article.

8

OX40 stimulation and PD-L1 blockade synergistically augment HBV-specific CD4 T cells in patients with HBeAg-negative infection.

Jacobi FJ, Wild K, Smits M, Zoldan K, Csernalabics B, Flecken T, Lang J, Ehrenmann P, Emmerich F, Hofmann M, Thimme R, Neumann-Haefelin C, Boettler T. Jacobi FJ, et al. Among authors: flecken t. J Hepatol. 2019 Jun;70(6):1103-1113. doi: 10.1016/j.jhep.2019.02.016. Epub 2019 Feb 28. J Hepatol. 2019. PMID: 30826436

9

Immunobiology of hepatocellular carcinoma.

Flecken T, Spangenberg HC, Thimme R. Flecken T, et al. Langenbecks Arch Surg. 2012 Jun;397(5):673-80. doi: 10.1007/s00423-011-0783-x. Epub 2011 Apr 9. Langenbecks Arch Surg. 2012. PMID: 21479622 Review.

10

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

Alanio C, Nicoli F, Sultanik P, Flecken T, Perot B, Duffy D, Bianchi E, Lim A, Clave E, van Buuren MM, Schnuriger A, Johnsson K, Boussier J, Garbarg-Chenon A, Bousquet L, Mottez E, Schumacher TN, Toubert A, Appay V, Heshmati F, Thimme R, Pol S, Mallet V, Albert ML. Alanio C, et al. Among authors: flecken t. Elife. 2015 Nov 14;4:e07916. doi: 10.7554/eLife.07916. Elife. 2015. PMID: 26568315 Free PMC article.

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