Rebbeck RT - Search Results

1

Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic.

Batiste SM, Blackwell DJ, Kim K, Kryshtal DO, Gomez-Hurtado N, Rebbeck RT, Cornea RL, Johnston JN, Knollmann BC. Batiste SM, et al. Among authors: rebbeck rt. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4810-4815. doi: 10.1073/pnas.1816685116. Epub 2019 Feb 21. Proc Natl Acad Sci U S A. 2019. PMID: 30792355 Free PMC article.

2

S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.

Rebbeck RT, Nitu FR, Rohde D, Most P, Bers DM, Thomas DD, Cornea RL. Rebbeck RT, et al. J Biol Chem. 2016 Jul 22;291(30):15896-907. doi: 10.1074/jbc.M115.713107. Epub 2016 May 19. J Biol Chem. 2016. PMID: 27226555 Free PMC article.

3

High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels.

Rebbeck RT, Essawy MM, Nitu FR, Grant BD, Gillispie GD, Thomas DD, Bers DM, Cornea RL. Rebbeck RT, et al. SLAS Discov. 2017 Feb;22(2):176-186. doi: 10.1177/1087057116674312. Epub 2016 Oct 22. SLAS Discov. 2017. PMID: 27760856 Free PMC article.

4

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.

Walweel K, Gomez-Hurtado N, Rebbeck RT, Oo YW, Beard NA, Molenaar P, Dos Remedios C, van Helden DF, Cornea RL, Knollmann BC, Laver DR. Walweel K, et al. Among authors: rebbeck rt. J Mol Cell Cardiol. 2019 May;130:96-106. doi: 10.1016/j.yjmcc.2019.03.018. Epub 2019 Mar 27. J Mol Cell Cardiol. 2019. PMID: 30928430 Free PMC article.

5

The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of Na_V1.5 and RyR2 function.

Johnson CN, Pattanayek R, Potet F, Rebbeck RT, Blackwell DJ, Nikolaienko R, Sequeira V, Le Meur R, Radwański PB, Davis JP, Zima AV, Cornea RL, Damo SM, Györke S, George AL Jr, Knollmann BC. Johnson CN, et al. Among authors: rebbeck rt. Cell Calcium. 2019 Sep;82:102063. doi: 10.1016/j.ceca.2019.102063. Epub 2019 Jul 30. Cell Calcium. 2019. PMID: 31401388 Free PMC article.

6

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators.

Lindsay A, Baumann CW, Rebbeck RT, Yuen SL, Southern WM, Hodges JS, Cornea RL, Thomas DD, Ervasti JM, Lowe DA. Lindsay A, et al. Among authors: rebbeck rt. Skelet Muscle. 2020 Feb 1;10(1):3. doi: 10.1186/s13395-020-0221-2. Skelet Muscle. 2020. PMID: 32007101 Free PMC article.

7

RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca²⁺ assays.

Rebbeck RT, Singh DP, Janicek KA, Bers DM, Thomas DD, Launikonis BS, Cornea RL. Rebbeck RT, et al. Sci Rep. 2020 Feb 4;10(1):1791. doi: 10.1038/s41598-020-58461-1. Sci Rep. 2020. PMID: 32019969 Free PMC article.

8

The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor.

Nikolaienko R, Bovo E, Rebbeck RT, Kahn D, Thomas DD, Cornea RL, Zima AV. Nikolaienko R, et al. Among authors: rebbeck rt. Redox Biol. 2020 Oct;37:101729. doi: 10.1016/j.redox.2020.101729. Epub 2020 Sep 15. Redox Biol. 2020. PMID: 32980662 Free PMC article.

9

Met125 is essential for maintaining the structural integrity of calmodulin's C-terminal domain.

Nelson SED, Weber DK, Rebbeck RT, Cornea RL, Veglia G, Thomas DD. Nelson SED, et al. Among authors: rebbeck rt. Sci Rep. 2020 Dec 7;10(1):21320. doi: 10.1038/s41598-020-78270-w. Sci Rep. 2020. PMID: 33288831 Free PMC article.

10

CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes.

Simon M, Ko CY, Rebbeck RT, Baidar S, Cornea RL, Bers DM. Simon M, et al. Among authors: rebbeck rt. J Mol Cell Cardiol. 2021 Dec;161:53-61. doi: 10.1016/j.yjmcc.2021.08.002. Epub 2021 Aug 8. J Mol Cell Cardiol. 2021. PMID: 34371035 Free PMC article.

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