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Page 1
Quality Control of Therapeutic Peptides by 1H NMR HiFSA Sequencing.
Choules MP, Bisson J, Gao W, Lankin DC, McAlpine JB, Niemitz M, Jaki BU, Franzblau SG, Pauli GF. Choules MP, et al. J Org Chem. 2019 Mar 15;84(6):3055-3073. doi: 10.1021/acs.joc.8b02704. Epub 2019 Feb 22. J Org Chem. 2019. PMID: 30793905 Free PMC article.
NMR reveals an undeclared constituent in custom synthetic peptides.
Choules MP, Bisson J, Simmler C, McAlpine JB, Giancaspro G, Bzhelyansky A, Niemitz M, Pauli GF. Choules MP, et al. J Pharm Biomed Anal. 2020 Jan 30;178:112915. doi: 10.1016/j.jpba.2019.112915. Epub 2019 Oct 10. J Pharm Biomed Anal. 2020. PMID: 31671336 Free PMC article.
Structural Sequencing of Oligopeptides Aided by 1H Iterative Full-Spin Analysis.
Gao W, McAlpine JB, Choules MP, Napolitano JG, Lankin DC, Simmler C, Ho NA, Lee H, Suh JW, Burton IW, Cho S, Franzblau SG, Chen SN, Pauli GF. Gao W, et al. Among authors: choules mp. J Nat Prod. 2017 Oct 27;80(10):2630-2643. doi: 10.1021/acs.jnatprod.7b00207. Epub 2017 Oct 16. J Nat Prod. 2017. PMID: 29035048
Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources.
Grzelak EM, Hwang C, Cai G, Nam JW, Choules MP, Gao W, Lankin DC, McAlpine JB, Mulugeta SG, Napolitano JG, Suh JW, Yang SH, Cheng J, Lee H, Kim JY, Cho SH, Pauli GF, Franzblau SG, Jaki BU. Grzelak EM, et al. Among authors: choules mp. ACS Infect Dis. 2016 Apr 8;2(4):294-301. doi: 10.1021/acsinfecdis.5b00150. Epub 2016 Feb 23. ACS Infect Dis. 2016. PMID: 27478868 Free PMC article.
Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening.
Grzelak EM, Choules MP, Gao W, Cai G, Wan B, Wang Y, McAlpine JB, Cheng J, Jin Y, Lee H, Suh JW, Pauli GF, Franzblau SG, Jaki BU, Cho S. Grzelak EM, et al. Among authors: choules mp. J Antibiot (Tokyo). 2019 Oct;72(10):719-728. doi: 10.1038/s41429-019-0205-9. Epub 2019 Jul 11. J Antibiot (Tokyo). 2019. PMID: 31292530 Free PMC article. Review.
Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus.
Choules MP, Wolf NM, Lee H, Anderson JR, Grzelak EM, Wang Y, Ma R, Gao W, McAlpine JB, Jin YY, Cheng J, Lee H, Suh JW, Duc NM, Paik S, Choe JH, Jo EK, Chang CL, Lee JS, Jaki BU, Pauli GF, Franzblau SG, Cho S. Choules MP, et al. Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02204-18. doi: 10.1128/AAC.02204-18. Print 2019 Mar. Antimicrob Agents Chemother. 2019. PMID: 30602512 Free PMC article.
High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads.
Wolf NM, Lee H, Choules MP, Pauli GF, Phansalkar R, Anderson JR, Gao W, Ren J, Santarsiero BD, Lee H, Cheng J, Jin YY, Ho NA, Duc NM, Suh JW, Abad-Zapatero C, Cho S. Wolf NM, et al. Among authors: choules mp. ACS Infect Dis. 2019 Jun 14;5(6):829-840. doi: 10.1021/acsinfecdis.8b00276. Epub 2019 May 3. ACS Infect Dis. 2019. PMID: 30990022 Free PMC article.
13 results