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Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Donohoe G, Gill M, Corvin A, Morris DW. Harold D, et al. Among authors: walters j. Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002/ajmg.b.32716. Epub 2019 Feb 23. Am J Med Genet B Neuropsychiatr Genet. 2019. PMID: 30801977 Free PMC article.
Endophenotypes in psychiatric genetics.
Walters JT, Owen MJ. Walters JT, et al. Mol Psychiatry. 2007 Oct;12(10):886-90. doi: 10.1038/sj.mp.4002068. Mol Psychiatry. 2007. PMID: 17895920 Review. No abstract available.
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, Jones I, Forty L, Jones L, Gordon-Smith K, Riley B, O'Neill FA, Kendler KS, Sklar P, Purcell S, Kranz J; Schizophrenia Psychiatric Genome-wide Association Study Consortium; Wellcome Trust Case Control Consortium+; Wellcome Trust Case Control Consortium 2; Morris D, Gill M, Holmans P, Craddock N, Corvin A, Owen MJ, O'Donovan MC. Hamshere ML, et al. Among authors: walters jt. Mol Psychiatry. 2013 Jun;18(6):708-12. doi: 10.1038/mp.2012.67. Epub 2012 May 22. Mol Psychiatry. 2013. PMID: 22614287 Free PMC article.
Evidence that duplications of 22q11.2 protect against schizophrenia.
Rees E, Kirov G, Sanders A, Walters JT, Chambert KD, Shi J, Szatkiewicz J, O'Dushlaine C, Richards AL, Green EK, Jones I, Davies G, Legge SE, Moran JL, Pato C, Pato M, Genovese G, Levinson D, Duan J, Moy W, Göring HH, Morris D, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium; Craddock N, Sklar P, Hultman C, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ. Rees E, et al. Among authors: walters jt. Mol Psychiatry. 2014 Jan;19(1):37-40. doi: 10.1038/mp.2013.156. Epub 2013 Nov 12. Mol Psychiatry. 2014. PMID: 24217254 Free PMC article.
Copy number variation in bipolar disorder.
Green EK, Rees E, Walters JT, Smith KG, Forty L, Grozeva D, Moran JL, Sklar P, Ripke S, Chambert KD, Genovese G, McCarroll SA, Jones I, Jones L, Owen MJ, O'Donovan MC, Craddock N, Kirov G. Green EK, et al. Among authors: walters jt. Mol Psychiatry. 2016 Jan;21(1):89-93. doi: 10.1038/mp.2014.174. Epub 2015 Jan 6. Mol Psychiatry. 2016. PMID: 25560756 Free PMC article.
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Legge SE, Hamshere ML, Ripke S, Pardinas AF, Goldstein JI, Rees E, Richards AL, Leonenko G, Jorskog LF; Clozapine-Induced Agranulocytosis Consortium; Chambert KD, Collier DA, Genovese G, Giegling I, Holmans P, Jonasdottir A, Kirov G, McCarroll SA, MacCabe JH, Mantripragada K, Moran JL, Neale BM, Stefansson H, Rujescu D, Daly MJ, Sullivan PF, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: walters jtr. Mol Psychiatry. 2017 Oct;22(10):1502-1508. doi: 10.1038/mp.2016.97. Epub 2016 Jul 12. Mol Psychiatry. 2017. PMID: 27400856 Free PMC article.
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Legge SE, Hamshere ML, Ripke S, Pardinas AF, Goldstein JI, Rees E, Richards AL, Leonenko G, Jorskog LF; Clozapine-Induced Agranulocytosis Consortium; Chambert KD, Collier DA, Genovese G, Giegling I, Holmans P, Jonasdottir A, Kirov G, McCarroll SA, MacCabe JH, Mantripragada K, Moran JL, Neale BM, Stefansson H, Rujescu D, Daly MJ, Sullivan PF, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: walters jtr. Mol Psychiatry. 2017 Oct;22(10):1509. doi: 10.1038/mp.2016.137. Epub 2016 Aug 9. Mol Psychiatry. 2017. PMID: 27502474 Free PMC article.
Schizophrenia copy number variants and associative learning.
Clifton NE, Pocklington AJ, Scholz B, Rees E, Walters JT, Kirov G, O'Donovan MC, Owen MJ, Wilkinson LS, Thomas KL, Hall J. Clifton NE, et al. Among authors: walters jt. Mol Psychiatry. 2017 Feb;22(2):178-182. doi: 10.1038/mp.2016.227. Epub 2016 Dec 13. Mol Psychiatry. 2017. PMID: 27956746 Free PMC article.
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Legge SE, Hamshere ML, Ripke S, Pardinas AF, Goldstein JI, Rees E, Richards AL, Leonenko G, Jorskog LF; Clozapine-Induced Agranulocytosis Consortium; Chambert KD, Collier DA, Genovese G, Giegling I, Holmans P, Jonasdottir A, Kirov G, McCarroll SA, MacCabe JH, Mantripragada K, Moran JL, Neale BM, Stefansson H, Rujescu D, Daly MJ, Sullivan PF, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: walters jtr. Mol Psychiatry. 2018 Jan;23(1):162-163. doi: 10.1038/mp.2017.214. Epub 2017 Oct 24. Mol Psychiatry. 2018. PMID: 29296025 Free PMC article.
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium; Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Pardiñas AF, et al. Among authors: walters jtr. Nat Genet. 2018 Mar;50(3):381-389. doi: 10.1038/s41588-018-0059-2. Epub 2018 Feb 26. Nat Genet. 2018. PMID: 29483656 Free PMC article.
1,484 results