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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.
David P, Drabczyk-Pluta M, Pastille E, Knuschke T, Werner T, Honke N, Megger DA, Akhmetzyanova I, Shaabani N, Eyking-Singer A, Cario E, Kershaw O, Gruber AD, Tenbusch M, Dietze KK, Trilling M, Liu J, Schadendorf D, Streeck H, Lang KS, Xie Y, Zimmer L, Sitek B, Paschen A, Westendorf AM, Dittmer U, Zelinskyy G. David P, et al. PLoS Pathog. 2020 Mar 30;16(3):e1008340. doi: 10.1371/journal.ppat.1008340. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32226027 Free PMC article.
Interleukin-3 protects against viral pneumonia in sepsis by enhancing plasmacytoid dendritic cell recruitment into the lungs and T cell priming.
Bénard A, Hansen FJ, Uhle F, Klösch B, Czubayko F, Mittelstädt A, Jacobsen A, David P, Podolska MJ, Anthuber A, Swierzy I, Schaack D, Mühl-Zürbes P, Steinkasserer A, Weyand M, Weigand MA, Brenner T, Krautz C, Grützmann R, Weber GF. Bénard A, et al. Among authors: david p. Front Immunol. 2023 Feb 22;14:1140630. doi: 10.3389/fimmu.2023.1140630. eCollection 2023. Front Immunol. 2023. PMID: 36911737 Free PMC article.
Exosomal ROR1 in peritoneal fluid identifies peritoneal disseminated PDAC and is associated with poor survival.
Mittelstädt A, Anthuber A, David P, Podolska M, Bénard A, Brunner M, Krautz C, Jacobsen A, Denz A, Weber K, Merkel S, Hackner D, Buniatov T, Roßdeutsch L, Klösch B, Swierzy I, Hansen FJ, Strobel D, Zopf Y, Baur JO, Van Deun J, Immanuel Geppert C, Gießl A, Lettmaier S, Semrau S, Grützmann R, Kouhestani D, Weber GF. Mittelstädt A, et al. Among authors: david p. Front Immunol. 2024 May 23;15:1253072. doi: 10.3389/fimmu.2024.1253072. eCollection 2024. Front Immunol. 2024. PMID: 38846943 Free PMC article.
Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections.
Bénard A, Jacobsen A, Brunner M, Krautz C, Klösch B, Swierzy I, Naschberger E, Podolska MJ, Kouhestani D, David P, Birkholz T, Castellanos I, Trufa D, Sirbu H, Vetter M, Kremer AE, Hildner K, Hecker A, Edinger F, Tenbusch M, Mühl-Zürbes P, Steinkasserer A, Richter E, Streeck H, Berger MM, Brenner T, Weigand MA, Swirski FK, Schett G, Grützmann R, Weber GF. Bénard A, et al. Among authors: david p. Nat Commun. 2021 Feb 18;12(1):1112. doi: 10.1038/s41467-021-21310-4. Nat Commun. 2021. PMID: 33602937 Free PMC article.
1,577 results