Brosch R - Search Results

1

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis.

Machelart A, Salzano G, Li X, Demars A, Debrie AS, Menendez-Miranda M, Pancani E, Jouny S, Hoffmann E, Deboosere N, Belhaouane I, Rouanet C, Simar S, Talahari S, Giannini V, Villemagne B, Flipo M, Brosch R, Nesslany F, Deprez B, Muraille E, Locht C, Baulard AR, Willand N, Majlessi L, Gref R, Brodin P. Machelart A, et al. Among authors: brosch r. ACS Nano. 2019 Apr 23;13(4):3992-4007. doi: 10.1021/acsnano.8b07902. Epub 2019 Mar 8. ACS Nano. 2019. PMID: 30822386 Free PMC article.

2

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant.

Brodin P, Eiglmeier K, Marmiesse M, Billault A, Garnier T, Niemann S, Cole ST, Brosch R. Brodin P, et al. Among authors: brosch r. Infect Immun. 2002 Oct;70(10):5568-78. doi: 10.1128/IAI.70.10.5568-5578.2002. Infect Immun. 2002. PMID: 12228284 Free PMC article.

3

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti.

Pym AS, Brodin P, Brosch R, Huerre M, Cole ST. Pym AS, et al. Among authors: brosch r. Mol Microbiol. 2002 Nov;46(3):709-17. doi: 10.1046/j.1365-2958.2002.03237.x. Mol Microbiol. 2002. PMID: 12410828 Free article.

4

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.

Pym AS, Brodin P, Majlessi L, Brosch R, Demangel C, Williams A, Griffiths KE, Marchal G, Leclerc C, Cole ST. Pym AS, et al. Among authors: brosch r. Nat Med. 2003 May;9(5):533-9. doi: 10.1038/nm859. Epub 2003 Apr 14. Nat Med. 2003. PMID: 12692540

5

Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex.

Marmiesse M, Brodin P, Buchrieser C, Gutierrez C, Simoes N, Vincent V, Glaser P, Cole ST, Brosch R. Marmiesse M, et al. Among authors: brosch r. Microbiology (Reading). 2004 Feb;150(Pt 2):483-496. doi: 10.1099/mic.0.26662-0. Microbiology (Reading). 2004. PMID: 14766927 Free article.

6

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

Demangel C, Brodin P, Cockle PJ, Brosch R, Majlessi L, Leclerc C, Cole ST. Demangel C, et al. Among authors: brosch r. Infect Immun. 2004 Apr;72(4):2170-6. doi: 10.1128/IAI.72.4.2170-2176.2004. Infect Immun. 2004. PMID: 15039340 Free PMC article.

7

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens.

Brodin P, Majlessi L, Brosch R, Smith D, Bancroft G, Clark S, Williams A, Leclerc C, Cole ST. Brodin P, et al. Among authors: brosch r. J Infect Dis. 2004 Jul 1;190(1):115-22. doi: 10.1086/421468. Epub 2004 Jun 4. J Infect Dis. 2004. PMID: 15195250

8

ESAT-6 proteins: protective antigens and virulence factors?

Brodin P, Rosenkrands I, Andersen P, Cole ST, Brosch R. Brodin P, et al. Among authors: brosch r. Trends Microbiol. 2004 Nov;12(11):500-8. doi: 10.1016/j.tim.2004.09.007. Trends Microbiol. 2004. PMID: 15488391 Review.

9

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system.

Majlessi L, Brodin P, Brosch R, Rojas MJ, Khun H, Huerre M, Cole ST, Leclerc C. Majlessi L, et al. Among authors: brosch r. J Immunol. 2005 Mar 15;174(6):3570-9. doi: 10.4049/jimmunol.174.6.3570. J Immunol. 2005. PMID: 15749894

10

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.

Brodin P, de Jonge MI, Majlessi L, Leclerc C, Nilges M, Cole ST, Brosch R. Brodin P, et al. Among authors: brosch r. J Biol Chem. 2005 Oct 7;280(40):33953-9. doi: 10.1074/jbc.M503515200. Epub 2005 Jul 27. J Biol Chem. 2005. PMID: 16048998 Free article.

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