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RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade.
Heidegger S, Kreppel D, Bscheider M, Stritzke F, Nedelko T, Wintges A, Bek S, Fischer JC, Graalmann T, Kalinke U, Bassermann F, Haas T, Poeck H. Heidegger S, et al. Among authors: kalinke u. EBioMedicine. 2019 Mar;41:146-155. doi: 10.1016/j.ebiom.2019.02.056. Epub 2019 Mar 6. EBioMedicine. 2019. PMID: 30852164 Free PMC article.
TRADD protein is an essential component of the RIG-like helicase antiviral pathway.
Michallet MC, Meylan E, Ermolaeva MA, Vazquez J, Rebsamen M, Curran J, Poeck H, Bscheider M, Hartmann G, König M, Kalinke U, Pasparakis M, Tschopp J. Michallet MC, et al. Among authors: kalinke u. Immunity. 2008 May;28(5):651-61. doi: 10.1016/j.immuni.2008.03.013. Epub 2008 Apr 24. Immunity. 2008. PMID: 18439848 Free article.
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G. Poeck H, et al. Among authors: kalinke u. Nat Med. 2008 Nov;14(11):1256-63. doi: 10.1038/nm.1887. Epub 2008 Nov 2. Nat Med. 2008. PMID: 18978796
The European Regulatory Environment of RNA-Based Vaccines.
Hinz T, Kallen K, Britten CM, Flamion B, Granzer U, Hoos A, Huber C, Khleif S, Kreiter S, Rammensee HG, Sahin U, Singh-Jasuja H, Türeci Ö, Kalinke U. Hinz T, et al. Among authors: kalinke u. Methods Mol Biol. 2017;1499:203-222. doi: 10.1007/978-1-4939-6481-9_13. Methods Mol Biol. 2017. PMID: 27987152 Review.
RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury.
Fischer JC, Bscheider M, Eisenkolb G, Lin CC, Wintges A, Otten V, Lindemans CA, Heidegger S, Rudelius M, Monette S, Porosnicu Rodriguez KA, Calafiore M, Liebermann S, Liu C, Lienenklaus S, Weiss S, Kalinke U, Ruland J, Peschel C, Shono Y, Docampo M, Velardi E, Jenq RR, Hanash AM, Dudakov JA, Haas T, van den Brink MRM, Poeck H. Fischer JC, et al. Among authors: kalinke u. Sci Transl Med. 2017 Apr 19;9(386):eaag2513. doi: 10.1126/scitranslmed.aag2513. Sci Transl Med. 2017. PMID: 28424327 Free PMC article.
262 results