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Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination.
Saez Cabodevilla J , Volbeda A , Hamelin O , Latour JM , Gigarel O , Clémancey M , Darnault C , Reichmann D , Amara P , Fontecilla-Camps JC , Ollagnier de Choudens S . Saez Cabodevilla J , et al. Among authors: latour jm. Chem Commun (Camb). 2019 Mar 26;55(26):3725-3728. doi: 10.1039/c8cc09023h. Chem Commun (Camb). 2019. PMID: 30855610
Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase.
Arragain S, Garcia-Serres R, Blondin G, Douki T, Clemancey M, Latour JM, Forouhar F, Neely H, Montelione GT, Hunt JF, Mulliez E, Fontecave M, Atta M. Arragain S, et al. Among authors: latour jm. J Biol Chem. 2010 Feb 19;285(8):5792-801. doi: 10.1074/jbc.M109.065516. Epub 2009 Dec 9. J Biol Chem. 2010. PMID: 20007320 Free PMC article.
Studies of inhibitor binding to the [4Fe-4S] cluster of quinolinate synthase.
Chan A, Clémancey M, Mouesca JM, Amara P, Hamelin O, Latour JM, Ollagnier de Choudens S. Chan A, et al. Among authors: latour jm. Angew Chem Int Ed Engl. 2012 Jul 27;51(31):7711-4. doi: 10.1002/anie.201202261. Epub 2012 Jun 19. Angew Chem Int Ed Engl. 2012. PMID: 22715136
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate.
Perche-Letuvée P, Kathirvelu V, Berggren G, Clemancey M, Latour JM, Maurel V, Douki T, Armengaud J, Mulliez E, Fontecave M, Garcia-Serres R, Gambarelli S, Atta M. Perche-Letuvée P, et al. Among authors: latour jm. J Biol Chem. 2012 Nov 30;287(49):41174-85. doi: 10.1074/jbc.M112.405019. Epub 2012 Oct 5. J Biol Chem. 2012. PMID: 23043105 Free PMC article.
A cyclic peptide-based redox-active model of rubredoxin.
Jacques A, Clémancey M, Blondin G, Fourmond V, Latour JM, Sénèque O. Jacques A, et al. Among authors: latour jm. Chem Commun (Camb). 2013 Apr 11;49(28):2915-7. doi: 10.1039/c3cc40517f. Chem Commun (Camb). 2013. PMID: 23459993
306 results