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Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro.
Saborowski A, Wolff K, Spielberg S, Beer B, Hartleben B, Erlangga Z, Becker D, Dow LE, Marhenke S, Woller N, Unger K, Schirmacher P, Manns MP, Marquardt JU, Vogel A, Saborowski M. Saborowski A, et al. Among authors: dow le. Hepatol Commun. 2019 Feb 5;3(3):423-436. doi: 10.1002/hep4.1312. eCollection 2019 Mar. Hepatol Commun. 2019. PMID: 30859153 Free PMC article.
A modular and flexible ESC-based mouse model of pancreatic cancer.
Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: dow le. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.
Modeling Disease In Vivo With CRISPR/Cas9.
Dow LE. Dow LE. Trends Mol Med. 2015 Oct;21(10):609-621. doi: 10.1016/j.molmed.2015.07.006. Trends Mol Med. 2015. PMID: 26432018 Free PMC article. Review.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
Annunziato S, Lutz C, Henneman L, Bhin J, Wong K, Siteur B, van Gerwen B, de Korte-Grimmerink R, Zafra MP, Schatoff EM, Drenth AP, van der Burg E, Eijkman T, Mukherjee S, Boroviak K, Wessels LF, van de Ven M, Huijbers IJ, Adams DJ, Dow LE, Jonkers J. Annunziato S, et al. Among authors: dow le. EMBO J. 2020 Mar 2;39(5):e102169. doi: 10.15252/embj.2019102169. Epub 2020 Jan 13. EMBO J. 2020. PMID: 31930530 Free PMC article.
Oncogenic context shapes the fitness landscape of tumor suppression.
Blair LM, Juan JM, Sebastian L, Tran VB, Nie W, Wall GD, Gerceker M, Lai IK, Apilado EA, Grenot G, Amar D, Foggetti G, Do Carmo M, Ugur Z, Deng D, Chenchik A, Paz Zafra M, Dow LE, Politi K, MacQuitty JJ, Petrov DA, Winslow MM, Rosen MJ, Winters IP. Blair LM, et al. Among authors: dow le. Nat Commun. 2023 Oct 12;14(1):6422. doi: 10.1038/s41467-023-42156-y. Nat Commun. 2023. PMID: 37828026 Free PMC article.
89 results