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Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. Farrelly LA, et al. Among authors: shen l. Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867594 Free PMC article.
TGM2-mediated histone transglutamination is dictated by steric accessibility.
Lukasak BJ, Mitchener MM, Kong L, Dul BE, Lazarus CD, Ramakrishnan A, Ni J, Shen L, Maze I, Muir TW. Lukasak BJ, et al. Among authors: shen l. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2208672119. doi: 10.1073/pnas.2208672119. Epub 2022 Oct 18. Proc Natl Acad Sci U S A. 2022. PMID: 36256821 Free PMC article.
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X. Wan L, et al. Among authors: shen l. Nature. 2017 Mar 9;543(7644):265-269. doi: 10.1038/nature21687. Epub 2017 Mar 1. Nature. 2017. PMID: 28241141 Free PMC article.
Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium.
Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EYM, Loh YE, Ding J, Shen L, Xu PX. Li J, et al. Among authors: shen l. Nucleic Acids Res. 2020 Apr 6;48(6):2880-2896. doi: 10.1093/nar/gkaa012. Nucleic Acids Res. 2020. PMID: 31956913 Free PMC article.
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