Roller A - Search Results

1

A Dogma in Doubt: Hydrolysis of Equatorial Ligands of Pt^IV Complexes under Physiological Conditions.

Kastner A, Poetsch I, Mayr J, Burda JV, Roller A, Heffeter P, Keppler BK, Kowol CR. Kastner A, et al. Among authors: roller a. Angew Chem Int Ed Engl. 2019 May 27;58(22):7464-7469. doi: 10.1002/anie.201900682. Epub 2019 Apr 25. Angew Chem Int Ed Engl. 2019. PMID: 30870571 Free PMC article.

2

Tumor-targeting of EGFR inhibitors by hypoxia-mediated activation.

Karnthaler-Benbakka C, Groza D, Kryeziu K, Pichler V, Roller A, Berger W, Heffeter P, Kowol CR. Karnthaler-Benbakka C, et al. Among authors: roller a. Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12930-12935. doi: 10.1002/anie.201403936. Epub 2014 Jul 30. Angew Chem Int Ed Engl. 2014. PMID: 25079700 Free PMC article.

3

An albumin-based tumor-targeted oxaliplatin prodrug with distinctly improved anticancer activity in vivo.

Mayr J, Heffeter P, Groza D, Galvez L, Koellensperger G, Roller A, Alte B, Haider M, Berger W, Kowol CR, Keppler BK. Mayr J, et al. Among authors: roller a. Chem Sci. 2017 Mar 1;8(3):2241-2250. doi: 10.1039/c6sc03862j. Epub 2016 Dec 15. Chem Sci. 2017. PMID: 28507680 Free PMC article.

4

Improving the Stability of Maleimide-Thiol Conjugation for Drug Targeting.

Lahnsteiner M, Kastner A, Mayr J, Roller A, Keppler BK, Kowol CR. Lahnsteiner M, et al. Among authors: roller a. Chemistry. 2020 Dec 4;26(68):15867-15870. doi: 10.1002/chem.202003951. Epub 2020 Oct 27. Chemistry. 2020. PMID: 32871016 Free PMC article.

5

Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase.

Kowol CR, Berger R, Eichinger R, Roller A, Jakupec MA, Schmidt PP, Arion VB, Keppler BK. Kowol CR, et al. Among authors: roller a. J Med Chem. 2007 Mar 22;50(6):1254-65. doi: 10.1021/jm0612618. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315858

6

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

Kowol CR, Trondl R, Heffeter P, Arion VB, Jakupec MA, Roller A, Galanski MS, Berger W, Keppler BK. Kowol CR, et al. Among authors: roller a. J Med Chem. 2009 Aug 27;52(16):5032-43. doi: 10.1021/jm900528d. J Med Chem. 2009. PMID: 19637923

7

A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.

Varbanov HP, Göschl S, Heffeter P, Theiner S, Roller A, Jensen F, Jakupec MA, Berger W, Galanski MS, Keppler BK. Varbanov HP, et al. Among authors: roller a. J Med Chem. 2014 Aug 14;57(15):6751-64. doi: 10.1021/jm500791c. Epub 2014 Jul 30. J Med Chem. 2014. PMID: 25032896 Free PMC article.

8

Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity.

Kowol CR, Nagy NV, Jakusch T, Roller A, Heffeter P, Keppler BK, Enyedy ÉA. Kowol CR, et al. Among authors: roller a. J Inorg Biochem. 2015 Nov;152:62-73. doi: 10.1016/j.jinorgbio.2015.08.023. Epub 2015 Sep 1. J Inorg Biochem. 2015. PMID: 26349014

9

Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes.

Terenzi A, Lötsch D, van Schoonhoven S, Roller A, Kowol CR, Berger W, Keppler BK, Barone G. Terenzi A, et al. Among authors: roller a. Dalton Trans. 2016 May 4;45(18):7758-67. doi: 10.1039/c6dt00648e. Dalton Trans. 2016. PMID: 27054617 Free PMC article.

10

Impact of the equatorial coordination sphere on the rate of reduction, lipophilicity and cytotoxic activity of platinum(IV) complexes.

Höfer D, Varbanov HP, Hejl M, Jakupec MA, Roller A, Galanski MS, Keppler BK. Höfer D, et al. Among authors: roller a. J Inorg Biochem. 2017 Sep;174:119-129. doi: 10.1016/j.jinorgbio.2017.06.005. Epub 2017 Jun 16. J Inorg Biochem. 2017. PMID: 28666155

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