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Page 1
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability.
Cacace R, Heeman B, Van Mossevelde S, De Roeck A, Hoogmartens J, De Rijk P, Gossye H, De Vos K, De Coster W, Strazisar M, De Baets G, Schymkowitz J, Rousseau F, Geerts N, De Pooter T, Peeters K, Sieben A, Martin JJ, Engelborghs S, Salmon E, Santens P, Vandenberghe R, Cras P, P De Deyn P, C van Swieten J, M van Duijn C, van der Zee J, Sleegers K, Van Broeckhoven C; BELNEU Consortium. Cacace R, et al. Among authors: de roeck a, de coster w, de pooter t, de baets g, de rijk p, de vos k. Acta Neuropathol. 2019 Jun;137(6):901-918. doi: 10.1007/s00401-019-01976-3. Epub 2019 Mar 14. Acta Neuropathol. 2019. PMID: 30874922 Free PMC article.
RuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTD.
Webster CP, Hall B, Crossley OM, Dauletalina D, King M, Lin YH, Castelli LM, Yang ZL, Coldicott I, Kyrgiou-Balli E, Higginbottom A, Ferraiuolo L, De Vos KJ, Hautbergue GM, Shaw PJ, West RJ, Azzouz M. Webster CP, et al. Among authors: de vos kj. Life Sci Alliance. 2024 Dec 5;8(2):e202402757. doi: 10.26508/lsa.202402757. Print 2025 Feb. Life Sci Alliance. 2024. PMID: 39638345 Free PMC article.
Corrigendum to "Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells" [Biochem. Pharmacol. 227 (2024) 116445].
De Vos K, Mavrogiannis A, Wolters JC, Schlenner S, Wierda K, Calabuig ÁC, Chinnaraj R, Dermesrobian V, Armoudjian Y, Jacquemyn M, Corthout N, Daelemans D, Annaert P. De Vos K, et al. Biochem Pharmacol. 2024 Nov;229:116497. doi: 10.1016/j.bcp.2024.116497. Epub 2024 Aug 22. Biochem Pharmacol. 2024. PMID: 39178689 No abstract available.
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells.
De Vos K, Mavrogiannis A, Wolters JC, Schlenner S, Wierda K, Cortés Calabuig Á, Chinnaraj R, Dermesrobian V, Armoudjian Y, Jacquemyn M, Corthout N, Daelemans D, Annaert P. De Vos K, et al. Biochem Pharmacol. 2024 Sep;227:116445. doi: 10.1016/j.bcp.2024.116445. Epub 2024 Jul 23. Biochem Pharmacol. 2024. PMID: 39053638
Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds.
Vanmarcke G, Sai-Hong Chui J, Cooreman A, De Vos K, Cleuren L, Van Rossom R, García-Llorens G, Izuel Idoype T, Boon R, Kumar Gautam M, Castell JV, Annaert P, Lluis F, Verfaillie CM. Vanmarcke G, et al. Among authors: de vos k. Stem Cells. 2023 Nov 5;41(11):1076-1088. doi: 10.1093/stmcls/sxad065. Stem Cells. 2023. PMID: 37616601
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.
Castelli LM, Lin YH, Sanchez-Martinez A, Gül A, Mohd Imran K, Higginbottom A, Upadhyay SK, Márkus NM, Rua Martins R, Cooper-Knock J, Montmasson C, Cohen R, Walton A, Bauer CS, De Vos KJ, Mead RJ, Azzouz M, Dominguez C, Ferraiuolo L, Shaw PJ, Whitworth AJ, Hautbergue GM. Castelli LM, et al. Among authors: de vos kj. Sci Transl Med. 2023 Mar;15(685):eabo3823. doi: 10.1126/scitranslmed.abo3823. Epub 2023 Mar 1. Sci Transl Med. 2023. PMID: 36857431
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin YH, Smith EF, Illanes-Álvarez F, Higginbottom A, Shaw PJ, Azzouz M, Ferraiuolo L, Hautbergue GM, Grierson AJ, De Vos KJ. Bauer CS, et al. Among authors: de vos kj. Front Cell Neurosci. 2022 Dec 16;16:1061559. doi: 10.3389/fncel.2022.1061559. eCollection 2022. Front Cell Neurosci. 2022. PMID: 36619668 Free PMC article.
64 results