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Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
Lenting K, Khurshed M, Peeters TH, van den Heuvel CNAM, van Lith SAM, de Bitter T, Hendriks W, Span PN, Molenaar RJ, Botman D, Verrijp K, Heerschap A, Ter Laan M, Kusters B, van Ewijk A, Huynen MA, van Noorden CJF, Leenders WPJ. Lenting K, et al. Among authors: huynen ma. FASEB J. 2019 Jan;33(1):557-571. doi: 10.1096/fj.201800907RR. Epub 2018 Jul 12. FASEB J. 2019. PMID: 30001166
The dependency on glutamate and lactate opens the way for novel approaches in the treatment of IDH(mut) gliomas.-Lenting, K., Khurshed, M., Peeters, T. H., van den Heuvel, C. N. A. M., van Lith, S. A. M., de Bitter, T., Hendriks, W., Span, P. ...J., Botman, D …
The dependency on glutamate and lactate opens the way for novel approaches in the treatment of IDH(mut) gliomas.-Lenting, K., Khurshed, M
RNA-based high-risk HPV genotyping and identification of high-risk HPV transcriptional activity in cervical tissues.
van den Heuvel CNAM, Loopik DL, Ebisch RMF, Elmelik D, Andralojc KM, Huynen M, Bulten J, Bekkers RLM, Massuger LFAG, Melchers WJG, Siebers AG, Leenders WPJ. van den Heuvel CNAM, et al. Among authors: huynen m. Mod Pathol. 2020 Apr;33(4):748-757. doi: 10.1038/s41379-019-0369-7. Epub 2019 Sep 19. Mod Pathol. 2020. PMID: 31537894 Free article.
Novel high-resolution targeted sequencing of the cervicovaginal microbiome.
Andralojc KM, Molina MA, Qiu M, Spruijtenburg B, Rasing M, Pater B, Huynen MA, Dutilh BE, Ederveen THA, Elmelik D, Siebers AG, Loopik D, Bekkers RLM, Leenders WPJ, Melchers WJG. Andralojc KM, et al. Among authors: huynen ma. BMC Biol. 2021 Dec 16;19(1):267. doi: 10.1186/s12915-021-01204-z. BMC Biol. 2021. PMID: 34915863 Free PMC article.
283 results