Davide J - Search Results

1

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.

Ng B, Cash-Mason T, Wang Y, Seitzer J, Burchard J, Brown D, Dudkin V, Davide J, Jadhav V, Sepp-Lorenzino L, Cejas PJ. Ng B, et al. Among authors: davide j. Mol Ther Nucleic Acids. 2019 Jun 7;16:194-205. doi: 10.1016/j.omtn.2019.02.013. Epub 2019 Feb 26. Mol Ther Nucleic Acids. 2019. PMID: 30901578 Free PMC article.

2

Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.

Abrams MT, Koser ML, Seitzer J, Williams SC, DiPietro MA, Wang W, Shaw AW, Mao X, Jadhav V, Davide JP, Burke PA, Sachs AB, Stirdivant SM, Sepp-Lorenzino L. Abrams MT, et al. Among authors: davide jp. Mol Ther. 2010 Jan;18(1):171-80. doi: 10.1038/mt.2009.208. Epub 2009 Sep 8. Mol Ther. 2010. PMID: 19738601 Free PMC article.

3

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L. Tao W, et al. Among authors: davide jp. Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13. Mol Ther. 2010. PMID: 20628357 Free PMC article.

4

Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.

Tao W, Mao X, Davide JP, Ng B, Cai M, Burke PA, Sachs AB, Sepp-Lorenzino L. Tao W, et al. Mol Ther. 2011 Mar;19(3):567-75. doi: 10.1038/mt.2010.282. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179008 Free PMC article.

5

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images.

Chen A, Dogdas B, Mehta S, Haskell K, Ng B, Keough E, Howell B, Meacham DA, Aslamkhan AG, Davide J, Stanton M, Bagchi A, Sepp-Lorenzino L, Tao W. Chen A, et al. Among authors: davide j. Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:3712-5. doi: 10.1109/EMBC.2012.6346773. Annu Int Conf IEEE Eng Med Biol Soc. 2012. PMID: 23366734

6

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.

Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, Sepp-Lorenzino L, Lobell RB. Tao W, et al. Among authors: davide jp. Cancer Cell. 2005 Jul;8(1):49-59. doi: 10.1016/j.ccr.2005.06.003. Cancer Cell. 2005. PMID: 16023598 Free article.

7

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.

Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB. Tao W, et al. Among authors: davide jp. Mol Cell Biol. 2007 Jan;27(2):689-98. doi: 10.1128/MCB.01505-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101792 Free PMC article.

8

Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.

Roecker AJ, Coleman PJ, Mercer SP, Schreier JD, Buser CA, Walsh ES, Hamilton K, Lobell RB, Tao W, Diehl RE, South VJ, Davide JP, Kohl NE, Yan Y, Kuo LC, Li C, Fernandez-Metzler C, Mahan EA, Prueksaritanont T, Hartman GD. Roecker AJ, et al. Among authors: davide jp. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5677-82. doi: 10.1016/j.bmcl.2007.07.074. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17766111

9

Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.

Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE. Lobell RB, et al. Among authors: davide jp. Mol Cancer Ther. 2002 Jul;1(9):747-58. Mol Cancer Ther. 2002. PMID: 12479371

10

A cell-based radioligand binding assay for farnesyl: protein transferase inhibitors.

Lobell RB, Davide JP, Kohl NE, Burns HD, Eng WS, Gibson RE. Lobell RB, et al. J Biomol Screen. 2003 Aug;8(4):430-8. doi: 10.1177/1087057103256153. J Biomol Screen. 2003. PMID: 14567795

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