Sepp-Lorenzino L - Search Results

1

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.

Ng B, Cash-Mason T, Wang Y, Seitzer J, Burchard J, Brown D, Dudkin V, Davide J, Jadhav V, Sepp-Lorenzino L, Cejas PJ. Ng B, et al. Among authors: sepp lorenzino l. Mol Ther Nucleic Acids. 2019 Jun 7;16:194-205. doi: 10.1016/j.omtn.2019.02.013. Epub 2019 Feb 26. Mol Ther Nucleic Acids. 2019. PMID: 30901578 Free PMC article.

2

Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.

Abrams MT, Koser ML, Seitzer J, Williams SC, DiPietro MA, Wang W, Shaw AW, Mao X, Jadhav V, Davide JP, Burke PA, Sachs AB, Stirdivant SM, Sepp-Lorenzino L. Abrams MT, et al. Mol Ther. 2010 Jan;18(1):171-80. doi: 10.1038/mt.2009.208. Epub 2009 Sep 8. Mol Ther. 2010. PMID: 19738601 Free PMC article.

3

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L. Tao W, et al. Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13. Mol Ther. 2010. PMID: 20628357 Free PMC article.

4

Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.

Tao W, Mao X, Davide JP, Ng B, Cai M, Burke PA, Sachs AB, Sepp-Lorenzino L. Tao W, et al. Mol Ther. 2011 Mar;19(3):567-75. doi: 10.1038/mt.2010.282. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179008 Free PMC article.

5

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth.

Khan T, Weber H, DiMuzio J, Matter A, Dogdas B, Shah T, Thankappan A, Disa J, Jadhav V, Lubbers L, Sepp-Lorenzino L, Strapps WR, Tadin-Strapps M. Khan T, et al. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e342. doi: 10.1038/mtna.2016.55. Mol Ther Nucleic Acids. 2016. PMID: 27483025 Free PMC article.

6

Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit.

Chen Z, Luo B, Cai TQ, Thankappan A, Xu Y, Wu W, DiMuzio J, Lifsted T, DiPietro M, Disa J, Ng B, Leander K, Clark S, Hoos L, Zhou Y, Jochnowitz N, Jachec C, Szczerba P, Gindy ME, Strapps W, Sepp-Lorenzino L, Seiffert DA, Lubbers L, Tadin-Strapps M. Chen Z, et al. Mol Ther Nucleic Acids. 2015 Jan 27;4(1):e224. doi: 10.1038/mtna.2014.75. Mol Ther Nucleic Acids. 2015. PMID: 25625614 Free PMC article.

7

Centyrin ligands for extrahepatic delivery of siRNA.

Klein D, Goldberg S, Theile CS, Dambra R, Haskell K, Kuhar E, Lin T, Parmar R, Manoharan M, Richter M, Wu M, Mendrola Zarazowski J, Jadhav V, Maier MA, Sepp-Lorenzino L, O'Neil K, Dudkin V. Klein D, et al. Among authors: sepp lorenzino l. Mol Ther. 2021 Jun 2;29(6):2053-2066. doi: 10.1016/j.ymthe.2021.02.015. Epub 2021 Feb 15. Mol Ther. 2021. PMID: 33601052 Free PMC article.

8

Quantitative evaluation of siRNA delivery in vivo.

Pei Y, Hancock PJ, Zhang H, Bartz R, Cherrin C, Innocent N, Pomerantz CJ, Seitzer J, Koser ML, Abrams MT, Xu Y, Kuklin NA, Burke PA, Sachs AB, Sepp-Lorenzino L, Barnett SF. Pei Y, et al. RNA. 2010 Dec;16(12):2553-63. doi: 10.1261/rna.2255810. Epub 2010 Oct 12. RNA. 2010. PMID: 20940339 Free PMC article.

9

Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images.

Chen A, Dogdas B, Mehta S, Haskell K, Ng B, Keough E, Howell B, Meacham DA, Aslamkhan AG, Davide J, Stanton M, Bagchi A, Sepp-Lorenzino L, Tao W. Chen A, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:3712-5. doi: 10.1109/EMBC.2012.6346773. Annu Int Conf IEEE Eng Med Biol Soc. 2012. PMID: 23366734

10

A single dose of EGLN1 siRNA yields increased erythropoiesis in nonhuman primates.

Abrams MT, Koser M, Burchard J, Strapps W, Mehmet H, Gindy M, Zaller D, Sepp-Lorenzino L, Stickens D. Abrams MT, et al. Nucleic Acid Ther. 2014 Dec;24(6):405-12. doi: 10.1089/nat.2014.0495. Nucleic Acid Ther. 2014. PMID: 25272050

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