Freudenthal BD - Search Results

1

Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase.

Akakpo JY, Ramachandran A, Duan L, Schaich MA, Jaeschke MW, Freudenthal BD, Ding WX, Rumack BH, Jaeschke H. Akakpo JY, et al. Among authors: freudenthal bd. Toxicol Sci. 2019 Jul 1;170(1):57-68. doi: 10.1093/toxsci/kfz077. Toxicol Sci. 2019. PMID: 30903181 Free PMC article.

2

Base excision repair of oxidative DNA damage: from mechanism to disease.

Whitaker AM, Schaich MA, Smith MR, Flynn TS, Freudenthal BD. Whitaker AM, et al. Among authors: freudenthal bd. Front Biosci (Landmark Ed). 2017 Mar 1;22(9):1493-1522. doi: 10.2741/4555. Front Biosci (Landmark Ed). 2017. PMID: 28199214 Free PMC article. Review.

3

Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.

Whitaker AM, Smith MR, Schaich MA, Freudenthal BD. Whitaker AM, et al. Among authors: freudenthal bd. Nucleic Acids Res. 2017 Jun 20;45(11):6934-6944. doi: 10.1093/nar/gkx293. Nucleic Acids Res. 2017. PMID: 28449123 Free PMC article.

4

Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues.

Schaich MA, Smith MR, Cloud AS, Holloran SM, Freudenthal BD. Schaich MA, et al. Among authors: freudenthal bd. Chem Res Toxicol. 2017 Nov 20;30(11):1993-2001. doi: 10.1021/acs.chemrestox.7b00173. Epub 2017 Sep 1. Chem Res Toxicol. 2017. PMID: 28862449 Free PMC article.

5

Specific mutations in the D1-D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors.

Bastola P, Wang F, Schaich MA, Gan T, Freudenthal BD, Chou TF, Chien J. Bastola P, et al. Among authors: freudenthal bd. Cell Death Discov. 2017 Nov 6;3:17065. doi: 10.1038/cddiscovery.2017.65. eCollection 2017. Cell Death Discov. 2017. PMID: 29367883 Free PMC article.

6

Structure and function relationships in mammalian DNA polymerases.

Hoitsma NM, Whitaker AM, Schaich MA, Smith MR, Fairlamb MS, Freudenthal BD. Hoitsma NM, et al. Among authors: freudenthal bd. Cell Mol Life Sci. 2020 Jan;77(1):35-59. doi: 10.1007/s00018-019-03368-y. Epub 2019 Nov 13. Cell Mol Life Sci. 2020. PMID: 31722068 Free PMC article. Review.

7

Mechanisms of nucleotide selection by telomerase.

Schaich MA, Sanford SL, Welfer GA, Johnson SA, Khoang TH, Opresko PL, Freudenthal BD. Schaich MA, et al. Among authors: freudenthal bd. Elife. 2020 Jun 5;9:e55438. doi: 10.7554/eLife.55438. Elife. 2020. PMID: 32501800 Free PMC article.

8

Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine.

Schnable BL, Schaich MA, Roginskaya V, Leary LP, Weaver TM, Freudenthal BD, Drohat AC, Van Houten B. Schnable BL, et al. Among authors: freudenthal bd. Nat Commun. 2024 Oct 25;15(1):9226. doi: 10.1038/s41467-024-53497-7. Nat Commun. 2024. PMID: 39455577 Free PMC article.

9

Optimal and variant metal-ion routes in DNA polymerase β's conformational pathways.

Li Y, Freudenthal BD, Beard WA, Wilson SH, Schlick T. Li Y, et al. Among authors: freudenthal bd. J Am Chem Soc. 2014 Mar 5;136(9):3630-9. doi: 10.1021/ja412701f. Epub 2014 Feb 21. J Am Chem Soc. 2014. PMID: 24511902 Free PMC article.

10

Revealing the role of the product metal in DNA polymerase β catalysis.

Perera L, Freudenthal BD, Beard WA, Pedersen LG, Wilson SH. Perera L, et al. Among authors: freudenthal bd. Nucleic Acids Res. 2017 Mar 17;45(5):2736-2745. doi: 10.1093/nar/gkw1363. Nucleic Acids Res. 2017. PMID: 28108654 Free PMC article.

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