Rumack BH - Search Results

1

Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase.

Akakpo JY, Ramachandran A, Duan L, Schaich MA, Jaeschke MW, Freudenthal BD, Ding WX, Rumack BH, Jaeschke H. Akakpo JY, et al. Among authors: rumack bh. Toxicol Sci. 2019 Jul 1;170(1):57-68. doi: 10.1093/toxsci/kfz077. Toxicol Sci. 2019. PMID: 30903181 Free PMC article.

2

Anaphylactoid Reactions to Intravenous N-Acetylcysteine during Treatment for Acetaminophen Poisoning.

Yarema M, Chopra P, Sivilotti MLA, Johnson D, Nettel-Aguirre A, Bailey B, Victorino C, Gosselin S, Purssell R, Thompson M, Spyker D, Rumack B. Yarema M, et al. J Med Toxicol. 2018 Jun;14(2):120-127. doi: 10.1007/s13181-018-0653-9. Epub 2018 Feb 8. J Med Toxicol. 2018. PMID: 29423816 Free PMC article.

3

4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes.

Akakpo JY, Ramachandran A, Kandel SE, Ni HM, Kumer SC, Rumack BH, Jaeschke H. Akakpo JY, et al. Among authors: rumack bh. Hum Exp Toxicol. 2018 Dec;37(12):1310-1322. doi: 10.1177/0960327118774902. Epub 2018 May 9. Hum Exp Toxicol. 2018. PMID: 29739258 Free PMC article.

4

Changing nomogram risk zone classification with serial testing after acute acetaminophen overdose: a retrospective database analysis.

Mutsaers A, Green JP, Sivilotti MLA, Yarema MC, Tucker D, Johnson DW, Spyker DA, Rumack BH. Mutsaers A, et al. Among authors: rumack bh. Clin Toxicol (Phila). 2019 Jun;57(6):380-386. doi: 10.1080/15563650.2018.1529320. Epub 2019 Jan 28. Clin Toxicol (Phila). 2019. PMID: 30689438

5

The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers.

Kang AM, Padilla-Jones A, Fisher ES, Akakpo JY, Jaeschke H, Rumack BH, Gerkin RD, Curry SC. Kang AM, et al. Among authors: rumack bh. J Med Toxicol. 2020 Apr;16(2):169-176. doi: 10.1007/s13181-019-00740-z. Epub 2019 Nov 25. J Med Toxicol. 2020. PMID: 31768936 Free PMC article. Clinical Trial.

6

The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study.

Monte AA, Sonn B, Saben J, Rumack BH, Reynolds KM, Dart RC, Heard KJ. Monte AA, et al. Among authors: rumack bh. J Med Toxicol. 2021 Apr;17(2):160-167. doi: 10.1007/s13181-020-00815-2. Epub 2020 Oct 13. J Med Toxicol. 2021. PMID: 33051802 Free PMC article.

7

4-methylpyrazole protects against acetaminophen-induced acute kidney injury.

Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H. Akakpo JY, et al. Among authors: rumack bh. Toxicol Appl Pharmacol. 2020 Dec 15;409:115317. doi: 10.1016/j.taap.2020.115317. Epub 2020 Nov 4. Toxicol Appl Pharmacol. 2020. PMID: 33157119 Free PMC article.

8

Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen.

Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Sonn BJ, et al. Among authors: rumack bh. Clin Toxicol (Phila). 2022 Feb;60(2):221-230. doi: 10.1080/15563650.2021.1925686. Epub 2021 May 28. Clin Toxicol (Phila). 2022. PMID: 34047639 Free PMC article.

9

Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole.

Akakpo JY, Jaeschke MW, Ramachandran A, Curry SC, Rumack BH, Jaeschke H. Akakpo JY, et al. Among authors: rumack bh. Arch Toxicol. 2021 Oct;95(10):3377-3391. doi: 10.1007/s00204-021-03142-9. Epub 2021 Aug 22. Arch Toxicol. 2021. PMID: 34420083 Free PMC article.

10

Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.

Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH. Link SL, et al. Among authors: rumack bh. Clin Toxicol (Phila). 2022 Apr;60(4):472-477. doi: 10.1080/15563650.2021.1996591. Epub 2021 Oct 28. Clin Toxicol (Phila). 2022. PMID: 34709101

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