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In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sun X, et al. Among authors: winter mc. Sci Transl Med. 2019 Mar 27;11(485):eaau7531. doi: 10.1126/scitranslmed.aau7531. Sci Transl Med. 2019. PMID: 30918114 Free PMC article.
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.
Tyler SR, Rotti PG, Sun X, Yi Y, Xie W, Winter MC, Flamme-Wiese MJ, Tucker BA, Mullins RF, Norris AW, Engelhardt JF. Tyler SR, et al. Among authors: winter mc. Cell Rep. 2019 Feb 12;26(7):1951-1964.e8. doi: 10.1016/j.celrep.2019.01.063. Cell Rep. 2019. PMID: 30759402 Free PMC article.
Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b.
Choi SH, Reeves RE, Romano Ibarra GS, Lynch TJ, Shahin WS, Feng Z, Gasser GN, Winter MC, Evans TIA, Liu X, Luo M, Zhang Y, Stoltz DA, Devor EJ, Yan Z, Engelhardt JF. Choi SH, et al. Among authors: winter mc. Genes (Basel). 2020 Oct 6;11(10):1169. doi: 10.3390/genes11101169. Genes (Basel). 2020. PMID: 33036232 Free PMC article.
CFTR represses a PDX1 axis to govern pancreatic ductal cell fate.
Rotti PG, Yi Y, Gasser G, Yuan F, Sun X, Apak-Evans I, Wu P, Liu G, Choi S, Reeves R, Scioneaux AE, Zhang Y, Winter M, Liang B, Cunicelli N, Uc A, Norris AW, Sussel L, Wells KL, Engelhardt JF. Rotti PG, et al. iScience. 2024 Nov 15;27(12):111393. doi: 10.1016/j.isci.2024.111393. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687022 Free PMC article.
Phosphate stimulates CFTR Cl- channels.
Carson MR, Travis SM, Winter MC, Sheppard DN, Welsh MJ. Carson MR, et al. Among authors: winter mc. Biophys J. 1994 Nov;67(5):1867-75. doi: 10.1016/S0006-3495(94)80668-X. Biophys J. 1994. PMID: 7532021 Free PMC article.
90 results