Li W - Search Results

1

Covalent modification of Cys-239 in β-tubulin by small molecules as a strategy to promote tubulin heterodimer degradation.

Yang J, Li Y, Yan W, Li W, Qiu Q, Ye H, Chen L. Yang J, et al. Among authors: li y, li w. J Biol Chem. 2019 May 17;294(20):8161-8170. doi: 10.1074/jbc.RA118.006325. Epub 2019 Apr 2. J Biol Chem. 2019. PMID: 30940730 Free PMC article.

2

Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells.

Yang J, Zhou Y, Cheng X, Fan Y, He S, Li S, Ye H, Xie C, Wu W, Li C, Pei H, Li L, Wei Z, Peng A, Wei Y, Li W, Chen L. Yang J, et al. Among authors: li s, li c, li w, li l. Sci Rep. 2015 Jan 9;5:7697. doi: 10.1038/srep07697. Sci Rep. 2015. PMID: 25571970 Free PMC article.

3

Liposomal honokiol induced lysosomal degradation of Hsp90 client proteins and protective autophagy in both gefitinib-sensitive and gefitinib-resistant NSCLC cells.

Yang J, Wu W, Wen J, Ye H, Luo H, Bai P, Tang M, Wang F, Zheng L, Yang S, Li W, Peng A, Yang L, Wan L, Chen L. Yang J, et al. Among authors: li w. Biomaterials. 2017 Oct;141:188-198. doi: 10.1016/j.biomaterials.2017.07.002. Epub 2017 Jul 4. Biomaterials. 2017. PMID: 28689115

4

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.

Yan W, Yang T, Yang J, Wang T, Yu Y, Wang Y, Chen Q, Bai P, Li D, Ye H, Qiu Q, Zhou Y, Hu Y, Yang S, Wei Y, Li W, Chen L. Yan W, et al. Among authors: li d, li w. Cell Physiol Biochem. 2018;47(2):489-504. doi: 10.1159/000489983. Epub 2018 May 22. Cell Physiol Biochem. 2018. PMID: 29794416 Free article.

5

Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis.

Zhang C, Pei H, He J, Zhu J, Li W, Niu T, Xiang M, Chen L. Zhang C, et al. Among authors: li w. Eur J Med Chem. 2019 May 1;169:121-143. doi: 10.1016/j.ejmech.2019.02.077. Epub 2019 Mar 6. Eur J Med Chem. 2019. PMID: 30875504

6

PEG-derivatized birinapant as a nanomicellar carrier of paclitaxel delivery for cancer therapy.

Shu X, Zhu Z, Cao D, Zheng L, Wang F, Pei H, Wen J, Yang J, Li D, Bai P, Tang M, Ye H, Peng A, Li W, Chen L. Shu X, et al. Among authors: li d, li w. Colloids Surf B Biointerfaces. 2019 Oct 1;182:110356. doi: 10.1016/j.colsurfb.2019.110356. Epub 2019 Jul 13. Colloids Surf B Biointerfaces. 2019. PMID: 31319226

7

X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors.

Arnst KE, Banerjee S, Wang Y, Chen H, Li Y, Yang L, Li W, Miller DD, Li W. Arnst KE, et al. Among authors: li y, li w. ACS Chem Biol. 2019 Dec 20;14(12):2810-2821. doi: 10.1021/acschembio.9b00696. Epub 2019 Nov 25. ACS Chem Biol. 2019. PMID: 31714738

8

Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.

Chen H, Deng S, Wang Y, Albadari N, Kumar G, Ma D, Li W, White SW, Miller DD, Li W. Chen H, et al. Among authors: li w. J Med Chem. 2020 Jan 23;63(2):827-846. doi: 10.1021/acs.jmedchem.9b01815. Epub 2020 Jan 7. J Med Chem. 2020. PMID: 31860298

9

Author Correction: Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells.

Yang J, Zhou Y, Cheng X, Fan Y, He S, Li S, Ye H, Xie C, Wu W, Li C, Pei H, Li L, Wei Z, Peng A, Wei Y, Li W, Chen L. Yang J, et al. Among authors: li s, li c, li w, li l. Sci Rep. 2020 Apr 20;10(1):6895. doi: 10.1038/s41598-020-62992-y. Sci Rep. 2020. PMID: 32313012 Free PMC article.

10

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect.

Yang J, Yu Y, Li Y, Yan W, Ye H, Niu L, Tang M, Wang Z, Yang Z, Pei H, Wei H, Zhao M, Wen J, Yang L, Ouyang L, Wei Y, Chen Q, Li W, Chen L. Yang J, et al. Among authors: li y, li w. Sci Adv. 2021 May 19;7(21):eabg4168. doi: 10.1126/sciadv.abg4168. Print 2021 May. Sci Adv. 2021. PMID: 34138737 Free PMC article.

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