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Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen.
Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L. Barkovskaya A, et al. Among authors: seip k. Mol Oncol. 2021 Aug;15(8):2026-2045. doi: 10.1002/1878-0261.12951. Epub 2021 May 1. Mol Oncol. 2021. PMID: 33759347 Free PMC article.
AXL inhibition improves BRAF-targeted treatment in melanoma.
Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K. Nyakas M, et al. Among authors: seip k. Sci Rep. 2022 Mar 24;12(1):5076. doi: 10.1038/s41598-022-09078-z. Sci Rep. 2022. PMID: 35332208 Free PMC article.
The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy.
Egeland EV, Seip K, Skourti E, Øy GF, Pettersen SJ, Pandya AD, Dahle MA, Haugen MH, Kristian A, Nakken S, Engebraaten O, Mælandsmo GM, Prasmickaite L. Egeland EV, et al. Among authors: seip k. Br J Cancer. 2024 Nov;131(10):1656-1667. doi: 10.1038/s41416-024-02875-5. Epub 2024 Oct 10. Br J Cancer. 2024. PMID: 39390250 Free PMC article.
37 results