Klein AD - Search Results

1

Role of proteases in dysfunctional placental vascular remodelling in preeclampsia.

Gutiérrez JA, Gómez I, Chiarello DI, Salsoso R, Klein AD, Guzmán-Gutiérrez E, Toledo F, Sobrevia L. Gutiérrez JA, et al. Among authors: klein ad. Biochim Biophys Acta Mol Basis Dis. 2020 Feb 1;1866(2):165448. doi: 10.1016/j.bbadis.2019.04.004. Epub 2019 Apr 5. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 30954558 Free article. Review.

2

Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.

Yañez MJ, Marín T, Balboa E, Klein AD, Alvarez AR, Zanlungo S. Yañez MJ, et al. Among authors: klein ad. Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165875. doi: 10.1016/j.bbadis.2020.165875. Epub 2020 Jun 6. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32522631 Free article. Review.

3

c-Abl activates RIPK3 signaling in Gaucher disease.

Yañez MJ, Campos F, Marín T, Klein AD, Futerman AH, Alvarez AR, Zanlungo S. Yañez MJ, et al. Among authors: klein ad. Biochim Biophys Acta Mol Basis Dis. 2021 May 1;1867(5):166089. doi: 10.1016/j.bbadis.2021.166089. Epub 2021 Feb 4. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33549745 Free article.

4

A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids.

Durán A, Priestman DA, Las Heras M, Rebolledo-Jaramillo B, Olguín V, Calderón JF, Zanlungo S, Gutiérrez J, Platt FM, Klein AD. Durán A, et al. Among authors: klein ad. Int J Mol Sci. 2023 Mar 3;24(5):4915. doi: 10.3390/ijms24054915. Int J Mol Sci. 2023. PMID: 36902345 Free PMC article.

5

Lysosomal vitamin E accumulation in Niemann-Pick type C disease.

Yévenes LF, Klein A, Castro JF, Marín T, Leal N, Leighton F, Alvarez AR, Zanlungo S. Yévenes LF, et al. Biochim Biophys Acta. 2012 Feb;1822(2):150-60. doi: 10.1016/j.bbadis.2011.11.009. Epub 2011 Nov 15. Biochim Biophys Acta. 2012. PMID: 22120593 Free article.

6

Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons.

Klein A, Maldonado C, Vargas LM, Gonzalez M, Robledo F, Perez de Arce K, Muñoz FJ, Hetz C, Alvarez AR, Zanlungo S. Klein A, et al. Neurobiol Dis. 2011 Jan;41(1):209-18. doi: 10.1016/j.nbd.2010.09.008. Epub 2010 Sep 29. Neurobiol Dis. 2011. PMID: 20883783

7

Controversies on the potential therapeutic use of rapamycin for treating a lysosomal cholesterol storage disease.

Calderón JF, Klein AD. Calderón JF, et al. Among authors: klein ad. Mol Genet Metab Rep. 2018 May 12;15:135-136. doi: 10.1016/j.ymgmr.2018.05.001. eCollection 2018 Jun. Mol Genet Metab Rep. 2018. PMID: 30023307 Free PMC article. No abstract available.

8

Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage.

Klein AD, González de la Vega J, Zanlungo S. Klein AD, et al. Int J Mol Sci. 2020 Mar 20;21(6):2127. doi: 10.3390/ijms21062127. Int J Mol Sci. 2020. PMID: 32244854 Free PMC article.

9

NPC1 as a Modulator of Disease Severity and Viral Entry of SARSCoV- 2.

Vial C, Calderón JF, Klein AD. Vial C, et al. Among authors: klein ad. Curr Mol Med. 2021;21(1):2-4. doi: 10.2174/1566524020666200713175426. Curr Mol Med. 2021. PMID: 32660402

10

Treating Niemann-Pick C lysosomal storage: approved and emerging approaches.

Klein AD, Eden ER, Zanlungo S. Klein AD, et al. Trends Mol Med. 2024 Dec 12:S1471-4914(24)00313-7. doi: 10.1016/j.molmed.2024.11.011. Online ahead of print. Trends Mol Med. 2024. PMID: 39672736 No abstract available.

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