McManus MT - Search Results

1

High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions.

Mues M, Karra L, Romero-Moya D, Wandler A, Hangauer MJ, Ksionda O, Thus Y, Lindenbergh M, Shannon K, McManus MT, Roose JP. Mues M, et al. Among authors: mcmanus mt. Cell Rep. 2019 Apr 9;27(2):631-647.e5. doi: 10.1016/j.celrep.2019.03.045. Cell Rep. 2019. PMID: 30970263 Free PMC article.

2

Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome.

Ku GM, Kim H, Vaughn IW, Hangauer MJ, Myung Oh C, German MS, McManus MT. Ku GM, et al. Among authors: mcmanus mt. Mol Endocrinol. 2012 Oct;26(10):1783-92. doi: 10.1210/me.2012-1176. Epub 2012 Aug 21. Mol Endocrinol. 2012. PMID: 22915829 Free PMC article.

3

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs.

Hangauer MJ, Vaughn IW, McManus MT. Hangauer MJ, et al. Among authors: mcmanus mt. PLoS Genet. 2013 Jun;9(6):e1003569. doi: 10.1371/journal.pgen.1003569. Epub 2013 Jun 20. PLoS Genet. 2013. PMID: 23818866 Free PMC article.

4

Discovering the complexity of the metazoan transcriptome.

Hangauer MJ, Carpenter S, McManus MT. Hangauer MJ, et al. Among authors: mcmanus mt. Genome Biol. 2014 Apr 29;15(4):112. doi: 10.1186/gb4172. Genome Biol. 2014. PMID: 25001157 Free PMC article.

5

Epigenetic and transcriptional determinants of the human breast.

Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, Heravi-Moussavi A, Moksa M, Mingay M, Hussainkhel A, Davis B, Nagarajan RP, Hong C, Echipare L, O'Geen H, Hangauer MJ, Cheng JB, Neel D, Hu D, McManus MT, Moore R, Mungall A, Ma Y, Plettner P, Ziv E, Wang T, Farnham PJ, Jones SJ, Marra MA, Tlsty TD, Costello JF, Hirst M. Gascard P, et al. Among authors: mcmanus mt. Nat Commun. 2015 Feb 18;6:6351. doi: 10.1038/ncomms7351. Nat Commun. 2015. PMID: 25690954 Free PMC article.

6

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.

Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A. Horiuchi D, et al. Among authors: mcmanus mt. Nat Med. 2016 Nov;22(11):1321-1329. doi: 10.1038/nm.4213. Epub 2016 Oct 24. Nat Med. 2016. PMID: 27775705 Free PMC article.

7

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Hangauer MJ, et al. Among authors: mcmanus mt. Nature. 2017 Nov 9;551(7679):247-250. doi: 10.1038/nature24297. Epub 2017 Nov 1. Nature. 2017. PMID: 29088702 Free PMC article.

8

miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling.

Hines MJ, Coffre M, Mudianto T, Panduro M, Wigton EJ, Tegla C, Osorio-Vasquez V, Kageyama R, Benhamou D, Perez O, Bajwa S, McManus MT, Ansel KM, Melamed D, Koralov SB. Hines MJ, et al. Among authors: mcmanus mt. Cell Rep. 2020 Dec 1;33(9):108436. doi: 10.1016/j.celrep.2020.108436. Cell Rep. 2020. PMID: 33264610 Free PMC article.

9

High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways.

Covarrubias S, Vollmers AC, Capili A, Boettcher M, Shulkin A, Correa MR, Halasz H, Robinson EK, O'Briain L, Vollmers C, Blau J, Katzman S, McManus MT, Carpenter S. Covarrubias S, et al. Among authors: mcmanus mt. Cell Rep. 2020 Dec 29;33(13):108541. doi: 10.1016/j.celrep.2020.108541. Cell Rep. 2020. PMID: 33378675 Free PMC article.

10

Small RNAs and immunity.

McManus MT. McManus MT. Immunity. 2004 Dec;21(6):747-56. doi: 10.1016/j.immuni.2004.11.007. Immunity. 2004. PMID: 15589164 Free article. Review.

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