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USP7: combining tools towards selectivity.
Gjonaj L , Sapmaz A , González-Prieto R , Vertegaal ACO , Flierman D , Ovaa H . Gjonaj L , et al. Among authors: vertegaal aco. Chem Commun (Camb). 2019 Apr 25;55(35):5075-5078. doi: 10.1039/c9cc00969h. Chem Commun (Camb). 2019. PMID: 30972393
Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation.
Sampadi B, Vermeulen S, Mišovic B, Boei JJ, Batth TS, Chang JG, Paulsen MT, Magnuson B, Schimmel J, Kool H, Olie CS, Everts B, Vertegaal ACO, Olsen JV, Ljungman M, Jeggo PA, Mullenders LHF, Vrieling H. Sampadi B, et al. Among authors: vertegaal aco. Cells. 2022 Nov 27;11(23):3794. doi: 10.3390/cells11233794. Cells. 2022. PMID: 36497055 Free PMC article.
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Mulder MP, Witting K, Berlin I, Pruneda JN, Wu KP, Chang JG, Merkx R, Bialas J, Groettrup M, Vertegaal AC, Schulman BA, Komander D, Neefjes J, El Oualid F, Ovaa H. Mulder MP, et al. Nat Chem Biol. 2016 Jul;12(7):523-30. doi: 10.1038/nchembio.2084. Epub 2016 May 16. Nat Chem Biol. 2016. PMID: 27182664 Free PMC article.
SUMO targets the APC/C to regulate transition from metaphase to anaphase.
Eifler K, Cuijpers SAG, Willemstein E, Raaijmakers JA, El Atmioui D, Ovaa H, Medema RH, Vertegaal ACO. Eifler K, et al. Among authors: vertegaal aco. Nat Commun. 2018 Mar 16;9(1):1119. doi: 10.1038/s41467-018-03486-4. Nat Commun. 2018. PMID: 29549242 Free PMC article.
Probing ubiquitin and SUMO conjugation and deconjugation.
Ovaa H, Vertegaal ACO. Ovaa H, et al. Among authors: vertegaal aco. Biochem Soc Trans. 2018 Apr 17;46(2):423-436. doi: 10.1042/BST20170086. Epub 2018 Mar 27. Biochem Soc Trans. 2018. PMID: 29588386 Review.
101 results