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Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection.
Hensley-McBain T, Wu MC, Manuzak JA, Cheu RK, Gustin A, Driscoll CB, Zevin AS, Miller CJ, Coronado E, Smith E, Chang J, Gale M Jr, Somsouk M, Burgener AD, Hunt PW, Hope TJ, Collier AC, Klatt NR. Hensley-McBain T, et al. Among authors: chang j. PLoS Pathog. 2019 Apr 11;15(4):e1007672. doi: 10.1371/journal.ppat.1007672. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30973942 Free PMC article.
Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
Fisher BS, Green RR, Brown RR, Wood MP, Hensley-McBain T, Fisher C, Chang J, Miller AD, Bosche WJ, Lifson JD, Mavigner M, Miller CJ, Gale M Jr, Silvestri G, Chahroudi A, Klatt NR, Sodora DL. Fisher BS, et al. Among authors: chang j. PLoS Pathog. 2018 Feb 21;14(2):e1006871. doi: 10.1371/journal.ppat.1006871. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29466439 Free PMC article.
Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.
Barrenas F, Raehtz K, Xu C, Law L, Green RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang J, Smith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr. Barrenas F, et al. Among authors: chang j. Nat Commun. 2019 Nov 8;10(1):5101. doi: 10.1038/s41467-019-12987-9. Nat Commun. 2019. PMID: 31704931 Free PMC article.
Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR. Chamcha V, et al. Among authors: chang j. Sci Transl Med. 2019 Nov 20;11(519):eaav1800. doi: 10.1126/scitranslmed.aav1800. Sci Transl Med. 2019. PMID: 31748228 Free PMC article.
Author Correction: Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.
Barrenas F, Raehtz K, Xu C, Law L, Green RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang J, Smith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr. Barrenas F, et al. Among authors: chang j. Nat Commun. 2019 Dec 13;10(1):5768. doi: 10.1038/s41467-019-13816-9. Nat Commun. 2019. PMID: 31836755 Free PMC article.
Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.
Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, Washington-Parks R, Galli V, Fuller DH, Santra S, Agy M, Pal R, Palermo RE, Tomaras GD, Shen X, LaBranche CC, Montefiori DC, Venzon DJ, Trinh HV, Rao M, Gale M Jr, Sekaly RP, Franchini G. Gorini G, et al. Among authors: chang j. PLoS Pathog. 2020 Mar 12;16(3):e1008377. doi: 10.1371/journal.ppat.1008377. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32163525 Free PMC article.
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy.
Barrenäs F, Hansen SG, Law L, Driscoll C, Green RR, Smith E, Chang J, Golez I, Urion T, Peng X, Whitmore L, Newhouse D, Hughes CM, Morrow D, Randall KT, Selseth AN, Ford JC, Gilbride RM, Randall BE, Ainslie E, Oswald K, Shoemaker R, Fast R, Bosche WJ, Axthelm MK, Fukazawa Y, Pavlakis GN, Felber BK, Fourati S, Sekaly RP, Lifson JD, Komorowski J, Kosmider E, Shao D, Song W, Edlefsen PT, Picker LJ, Gale M Jr. Barrenäs F, et al. Among authors: chang j. PLoS Pathog. 2021 Jul 6;17(7):e1009278. doi: 10.1371/journal.ppat.1009278. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34228762 Free PMC article.
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species.
Malouli D, Gilbride RM, Wu HL, Hwang JM, Maier N, Hughes CM, Newhouse D, Morrow D, Ventura AB, Law L, Tisoncik-Go J, Whitmore L, Smith E, Golez I, Chang J, Reed JS, Waytashek C, Weber W, Taher H, Uebelhoer LS, Womack JL, McArdle MR, Gao J, Papen CR, Lifson JD, Burwitz BJ, Axthelm MK, Smedley J, Früh K, Gale M Jr, Picker LJ, Hansen SG, Sacha JB. Malouli D, et al. Among authors: chang j. Cell Host Microbe. 2022 Sep 14;30(9):1207-1218.e7. doi: 10.1016/j.chom.2022.07.013. Epub 2022 Aug 17. Cell Host Microbe. 2022. PMID: 35981532 Free PMC article.
Functional genomic analysis of the 68-1 RhCMV-Mycobacteria tuberculosis vaccine reveals an IL-15 response signature that is conserved with vector attenuation.
Sung CJ, Whitmore LS, Smith E, Chang J, Tisoncik-Go J, Barber-Axthelm A, Selseth A, Feltham S, Ojha S, Hansen SG, Picker LJ, Gale M Jr. Sung CJ, et al. Among authors: chang j. Front Immunol. 2024 Oct 15;15:1460344. doi: 10.3389/fimmu.2024.1460344. eCollection 2024. Front Immunol. 2024. PMID: 39474415 Free PMC article.
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