Basile L - Search Results

1

Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.

Ronsisvalle S, Spadaro A, Tomasello B, Basile L, Panarello F, Franchini S, Renis M, Guccione S, Crascì L, Panico AM. Ronsisvalle S, et al. Among authors: basile l. Future Med Chem. 2019 Jun;11(11):1245-1258. doi: 10.4155/fmc-2018-0535. Epub 2019 Apr 12. Future Med Chem. 2019. PMID: 30974972

2

Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives.

Maggio B, Raffa D, Raimondi MV, Plescia F, Trincavelli ML, Martini C, Meneghetti F, Basile L, Guccione S, Daidone G. Maggio B, et al. Among authors: basile l. Eur J Med Chem. 2012 Aug;54:709-20. doi: 10.1016/j.ejmech.2012.06.028. Epub 2012 Jun 28. Eur J Med Chem. 2012. PMID: 22795832

3

Evaluation of imidazole-based compounds as heme oxygenase-1 inhibitors.

Sorrenti V, Guccione S, Di Giacomo C, Modica MN, Pittalà V, Acquaviva R, Basile L, Pappalardo M, Salerno L. Sorrenti V, et al. Among authors: basile l. Chem Biol Drug Des. 2012 Dec;80(6):876-86. doi: 10.1111/cbdd.12015. Epub 2012 Oct 9. Chem Biol Drug Des. 2012. PMID: 22882835

4

Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: synthesis, biological evaluation, and docking studies.

Basile L, Alvarez S, Blanco A, Santagati A, Granata G, Di Pietro P, Guccione S, Muñoz-Fernández MÁ. Basile L, et al. Eur J Med Chem. 2012 Nov;57:149-61. doi: 10.1016/j.ejmech.2012.09.005. Epub 2012 Sep 10. Eur J Med Chem. 2012. PMID: 23047231

5

Computational comparison of imidazoline association with the I2 binding site in human monoamine oxidases.

Basile L, Pappalardo M, Guccione S, Milardi D, Ramsay RR. Basile L, et al. J Chem Inf Model. 2014 Apr 28;54(4):1200-7. doi: 10.1021/ci400346k. Epub 2014 Apr 2. J Chem Inf Model. 2014. PMID: 24601544

6

Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism.

Pappalardo M, Shachaf N, Basile L, Milardi D, Zeidan M, Raiyn J, Guccione S, Rayan A. Pappalardo M, et al. Among authors: basile l. PLoS One. 2014 Oct 16;9(10):e109340. doi: 10.1371/journal.pone.0109340. eCollection 2014. PLoS One. 2014. PMID: 25330207 Free PMC article.

7

Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis.

Impellizzeri AA, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S. Impellizzeri AA, et al. Among authors: basile l. Front Behav Neurosci. 2015 May 8;9:92. doi: 10.3389/fnbeh.2015.00092. eCollection 2015. Front Behav Neurosci. 2015. PMID: 26005408 Free PMC article.

8

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.

Caraci F, Pappalardo G, Basile L, Giuffrida A, Copani A, Tosto R, Sinopoli A, Giuffrida ML, Pirrone E, Drago F, Pignatello R, Guccione S. Caraci F, et al. Among authors: basile l. Eur J Pharmacol. 2015 Oct 5;764:256-263. doi: 10.1016/j.ejphar.2015.07.015. Epub 2015 Jul 7. Eur J Pharmacol. 2015. PMID: 26162702

9

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

Carletta A, Tilborg A, Moineaux L, de Ruyck J, Basile L, Salerno L, Romeo G, Wouters J, Guccione S. Carletta A, et al. Among authors: basile l. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2015 Aug;71(Pt 4):447-54. doi: 10.1107/S2052520615010410. Epub 2015 Jul 14. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2015. PMID: 26208625

10

Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease.

Kurt BZ, Gazioglu I, Basile L, Sonmez F, Ginex T, Kucukislamoglu M, Guccione S. Kurt BZ, et al. Among authors: basile l. Eur J Med Chem. 2015 Sep 18;102:80-92. doi: 10.1016/j.ejmech.2015.07.005. Epub 2015 Jul 10. Eur J Med Chem. 2015. PMID: 26244990

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