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Page 1
Development of a defined approach for eye irritation or serious eye damage for neat liquids based on cosmetics Europe analysis of in vitro RhCE and BCOP test methods.
Alépée N, Adriaens E, Abo T, Bagley D, Desprez B, Hibatallah J, Mewes K, Pfannenbecker U, Sala À, Van Rompay AR, Verstraelen S, McNamee P. Alépée N, et al. Among authors: mcnamee p. Toxicol In Vitro. 2019 Sep;59:100-114. doi: 10.1016/j.tiv.2019.04.011. Epub 2019 Apr 11. Toxicol In Vitro. 2019. PMID: 30981694
Cosmetics Europe multi-laboratory pre-validation of the EpiOcular™ reconstituted human tissue test method for the prediction of eye irritation.
Pfannenbecker U, Bessou-Touya S, Faller C, Harbell J, Jacob T, Raabe H, Tailhardat M, Alépée N, De Smedt A, De Wever B, Jones P, Kaluzhny Y, Le Varlet B, McNamee P, Marrec-Fairley M, Van Goethem F. Pfannenbecker U, et al. Among authors: mcnamee p. Toxicol In Vitro. 2013 Mar;27(2):619-26. doi: 10.1016/j.tiv.2012.11.007. Epub 2012 Nov 16. Toxicol In Vitro. 2013. PMID: 23159500
Cosmetics Europe multi-laboratory pre-validation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritation.
Alépée N, Bessou-Touya S, Cotovio J, de Smedt A, de Wever B, Faller C, Jones P, Le Varlet B, Marrec-Fairley M, Pfannenbecker U, Tailhardat M, van Goethem F, McNamee P. Alépée N, et al. Among authors: mcnamee p. Toxicol In Vitro. 2013 Aug;27(5):1476-88. doi: 10.1016/j.tiv.2013.02.009. Epub 2013 Mar 20. Toxicol In Vitro. 2013. PMID: 23524228
Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.
Alépée N, Barroso J, De Smedt A, De Wever B, Hibatallah J, Klaric M, Mewes KR, Millet M, Pfannenbecker U, Tailhardat M, Templier M, McNamee P. Alépée N, et al. Among authors: mcnamee p. Toxicol In Vitro. 2015 Jun;29(4):741-61. doi: 10.1016/j.tiv.2015.02.005. Epub 2015 Feb 18. Toxicol In Vitro. 2015. PMID: 25701760
Development of a defined approach for eye irritation or serious eye damage for liquids, neat and in dilution, based on cosmetics Europe analysis of in vitro STE and BCOP test methods.
Alépée N, Adriaens E, Abo T, Bagley D, Desprez B, Hibatallah J, Mewes K, Pfannenbecker U, Sala À, Van Rompay AR, Verstraelen S, McNamee P. Alépée N, et al. Among authors: mcnamee p. Toxicol In Vitro. 2019 Jun;57:154-163. doi: 10.1016/j.tiv.2019.02.019. Epub 2019 Feb 26. Toxicol In Vitro. 2019. PMID: 30817952
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: mcnamee p. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods.
Adriaens E, Barroso J, Eskes C, Hoffmann S, McNamee P, Alépée N, Bessou-Touya S, De Smedt A, De Wever B, Pfannenbecker U, Tailhardat M, Zuang V. Adriaens E, et al. Among authors: mcnamee p. Arch Toxicol. 2014 Mar;88(3):701-23. doi: 10.1007/s00204-013-1156-8. Epub 2013 Dec 28. Arch Toxicol. 2014. PMID: 24374802 Free PMC article.
Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD).
Barroso J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J, Klaric M, Mewes KR, Millet M, Templier M, McNamee P. Barroso J, et al. Among authors: mcnamee p. Arch Toxicol. 2017 Feb;91(2):521-547. doi: 10.1007/s00204-016-1679-x. Epub 2016 Mar 21. Arch Toxicol. 2017. PMID: 26997338 Free PMC article. Review.
A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: eye irritation.
McNamee P, Hibatallah J, Costabel-Farkas M, Goebel C, Araki D, Dufour E, Hewitt NJ, Jones P, Kirst A, Le Varlet B, Macfarlane M, Marrec-Fairley M, Rowland J, Schellauf F, Scheel J. McNamee P, et al. Regul Toxicol Pharmacol. 2009 Jul;54(2):197-209. doi: 10.1016/j.yrtph.2009.04.004. Epub 2009 Apr 22. Regul Toxicol Pharmacol. 2009. PMID: 19393279 Free article.
209 results