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Page 1
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells.
Pirazzi C, Valenti L, Motta BM, Pingitore P, Hedfalk K, Mancina RM, Burza MA, Indiveri C, Ferro Y, Montalcini T, Maglio C, Dongiovanni P, Fargion S, Rametta R, Pujia A, Andersson L, Ghosal S, Levin M, Wiklund O, Iacovino M, Borén J, Romeo S. Pirazzi C, et al. Among authors: romeo s. Hum Mol Genet. 2014 Aug 1;23(15):4077-85. doi: 10.1093/hmg/ddu121. Epub 2014 Mar 25. Hum Mol Genet. 2014. PMID: 24670599 Free PMC article.
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.
Mancina RM, Spagnuolo R, Milano M, Brogneri S, Morrone A, Cosco C, Lazzaro V, Russo C, Ferro Y, Pingitore P, Pujia A, Montalcini T, Doldo P, Garieri P, Piodi L, Caprioli F, Valenti L, Romeo S. Mancina RM, et al. Among authors: romeo s. Inflamm Bowel Dis. 2016 Jan;22(1):134-40. doi: 10.1097/MIB.0000000000000569. Inflamm Bowel Dis. 2016. PMID: 26355465 Free PMC article.
DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection.
Burza MA, Motta BM, Mancina RM, Pingitore P, Pirazzi C, Lepore SM, Spagnuolo R, Doldo P, Russo C, Lazzaro V, Fischer J, Berg T, Aghemo A, Cheroni C, De Francesco R, Fargion S, Colombo M, Datz C, Stickel F, Valenti L, Romeo S. Burza MA, et al. Among authors: romeo s. Hepatology. 2016 Feb;63(2):418-27. doi: 10.1002/hep.28322. Epub 2015 Dec 18. Hepatology. 2016. PMID: 26517016 Free PMC article.
The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.
Donati B, Motta BM, Pingitore P, Meroni M, Pietrelli A, Alisi A, Petta S, Xing C, Dongiovanni P, del Menico B, Rametta R, Mancina RM, Badiali S, Fracanzani AL, Craxì A, Fargion S, Nobili V, Romeo S, Valenti L. Donati B, et al. Among authors: romeo s. Hepatology. 2016 Mar;63(3):787-98. doi: 10.1002/hep.28370. Epub 2016 Jan 14. Hepatology. 2016. PMID: 26605757
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.
Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, Borén J, Montalcini T, Pujia A, Wiklund O, Hindy G, Spagnuolo R, Motta BM, Pipitone RM, Craxì A, Fargion S, Nobili V, Käkelä P, Kärjä V, Männistö V, Pihlajamäki J, Reilly DF, Castro-Perez J, Kozlitina J, Valenti L, Romeo S. Mancina RM, et al. Among authors: romeo s. Gastroenterology. 2016 May;150(5):1219-1230.e6. doi: 10.1053/j.gastro.2016.01.032. Epub 2016 Feb 2. Gastroenterology. 2016. PMID: 26850495 Free PMC article.
PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis.
Pingitore P, Dongiovanni P, Motta BM, Meroni M, Lepore SM, Mancina RM, Pelusi S, Russo C, Caddeo A, Rossi G, Montalcini T, Pujia A, Wiklund O, Valenti L, Romeo S. Pingitore P, et al. Among authors: romeo s. Hum Mol Genet. 2016 Dec 1;25(23):5212-5222. doi: 10.1093/hmg/ddw341. Hum Mol Genet. 2016. PMID: 27742777 Free PMC article.
Proinsulin C-peptide modulates the expression of ERK1/2, type I collagen and RANKL in human osteoblast-like cells (Saos-2).
Russo C, Lazzaro V, Gazzaruso C, Maurotti S, Ferro Y, Pingitore P, Fumo F, Coppola A, Gallotti P, Zambianchi V, Fodaro M, Galliera E, Marazzi MG, Corsi Romanelli MM, Giannini S, Romeo S, Pujia A, Montalcini T. Russo C, et al. Among authors: romeo s. Mol Cell Endocrinol. 2017 Feb 15;442:134-141. doi: 10.1016/j.mce.2016.12.012. Epub 2016 Dec 20. Mol Cell Endocrinol. 2017. PMID: 28007656
513 results