Leon MA - Search Results

1

Acute B-Cell Inhibition by Soluble Antigen Arrays Is Valency-Dependent and Predicts Immunomodulation in Splenocytes.

Griffin JD, Leon MA, Salash JR, Shao M, Hartwell BL, Pickens CJ, Sestak JO, Berkland C. Griffin JD, et al. Among authors: leon ma. Biomacromolecules. 2019 May 13;20(5):2115-2122. doi: 10.1021/acs.biomac.9b00328. Epub 2019 May 2. Biomacromolecules. 2019. PMID: 30995843 Free PMC article.

2

Multivalent Soluble Antigen Arrays Exhibit High Avidity Binding and Modulation of B Cell Receptor-Mediated Signaling to Drive Efficacy against Experimental Autoimmune Encephalomyelitis.

Hartwell BL, Pickens CJ, Leon M, Berkland C. Hartwell BL, et al. Biomacromolecules. 2017 Jun 12;18(6):1893-1907. doi: 10.1021/acs.biomac.7b00335. Epub 2017 May 17. Biomacromolecules. 2017. PMID: 28474886 Free PMC article.

3

Practical Considerations, Challenges, and Limitations of Bioconjugation via Azide-Alkyne Cycloaddition.

Pickens CJ, Johnson SN, Pressnall MM, Leon MA, Berkland CJ. Pickens CJ, et al. Among authors: leon ma. Bioconjug Chem. 2018 Mar 21;29(3):686-701. doi: 10.1021/acs.bioconjchem.7b00633. Epub 2018 Feb 1. Bioconjug Chem. 2018. PMID: 29287474 Free PMC article. Review.

4

Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis.

Hartwell BL, Pickens CJ, Leon M, Northrup L, Christopher MA, Griffin JD, Martinez-Becerra F, Berkland C. Hartwell BL, et al. Among authors: leon m. J Autoimmun. 2018 Sep;93:76-88. doi: 10.1016/j.jaut.2018.06.006. Epub 2018 Jul 13. J Autoimmun. 2018. PMID: 30007842 Free PMC article.

5

Soluble Antigen Arrays for Selective Desensitization of Insulin-Reactive B Cells.

Leon MA, Wemlinger SM, Larson NR, Ruffalo JK, Sestak JO, Middaugh CR, Cambier JC, Berkland C. Leon MA, et al. Mol Pharm. 2019 Apr 1;16(4):1563-1572. doi: 10.1021/acs.molpharmaceut.8b01250. Epub 2019 Feb 25. Mol Pharm. 2019. PMID: 30681867 Free PMC article.

6

Antigen-Drug Conjugates as a Novel Therapeutic Class for the Treatment of Antigen-Specific Autoimmune Disorders.

Pickens CJ, Christopher MA, Leon MA, Pressnall MM, Johnson SN, Thati S, Sullivan BP, Berkland C. Pickens CJ, et al. Among authors: leon ma. Mol Pharm. 2019 Jun 3;16(6):2452-2461. doi: 10.1021/acs.molpharmaceut.9b00063. Epub 2019 May 14. Mol Pharm. 2019. PMID: 31083955 Free PMC article.

7

Soluble Antigen Arrays Displaying Mimotopes Direct the Response of Diabetogenic T Cells.

Leon MA, Firdessa-Fite R, Ruffalo JK, Pickens CJ, Sestak JO, Creusot RJ, Berkland C. Leon MA, et al. ACS Chem Biol. 2019 Jul 19;14(7):1436-1448. doi: 10.1021/acschembio.9b00090. Epub 2019 Jul 1. ACS Chem Biol. 2019. PMID: 31260253 Free PMC article.

8

Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes.

Firdessa-Fite R, Johnson SN, Leon MA, Khosravi-Maharlooei M, Baker RL, Sestak JO, Berkland C, Creusot RJ. Firdessa-Fite R, et al. Among authors: leon ma. Diabetes. 2021 Jun;70(6):1334-1346. doi: 10.2337/db20-0845. Epub 2021 Jan 19. Diabetes. 2021. PMID: 33468513 Free PMC article.

9

Soluble antigen arrays improve the efficacy and safety of peptide-based tolerogenic immunotherapy.

Firdessa-Fite R, Johnson SN, Leon MA, Sestak JO, Berkland C, Creusot RJ. Firdessa-Fite R, et al. Among authors: leon ma. bioRxiv [Preprint]. 2023 May 7:2023.05.05.539161. doi: 10.1101/2023.05.05.539161. bioRxiv. 2023. Update in: Front Immunol. 2024 Jun 12;15:1258369. doi: 10.3389/fimmu.2024.1258369. PMID: 37205572 Free PMC article. Updated. Preprint.

10

Soluble antigen arrays provide increased efficacy and safety over free peptides for tolerogenic immunotherapy.

Firdessa-Fite R, Johnson SN, Bechi Genzano C, Leon MA, Ku A, Ocampo Gonzalez FA, Milner JD, Sestak JO, Berkland C, Creusot RJ. Firdessa-Fite R, et al. Among authors: leon ma. Front Immunol. 2024 Jun 12;15:1258369. doi: 10.3389/fimmu.2024.1258369. eCollection 2024. Front Immunol. 2024. PMID: 38933266 Free PMC article.

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