Chen J - Search Results

1

Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis.

Byun S, Jung H, Chen J, Kim YC, Kim DH, Kong B, Guo G, Kemper B, Kemper JK. Byun S, et al. Among authors: chen j. J Biol Chem. 2019 May 31;294(22):8732-8744. doi: 10.1074/jbc.RA119.008360. Epub 2019 Apr 17. J Biol Chem. 2019. PMID: 30996006 Free PMC article.

2

BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination.

Jung H, Chen J, Hu X, Sun H, Wu SY, Chiang CM, Kemper B, Chen LF, Kemper JK. Jung H, et al. Among authors: chen j, chen lf. JCI Insight. 2020 Dec 8;6(1):e141640. doi: 10.1172/jci.insight.141640. JCI Insight. 2020. PMID: 33290278 Free PMC article.

3

Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.

Hu X, Dong X, Li G, Chen Y, Chen J, He X, Sun H, Kim DH, Kemper JK, Chen LF. Hu X, et al. Among authors: chen j, chen lf, chen y. JCI Insight. 2021 Apr 8;6(7):e143379. doi: 10.1172/jci.insight.143379. JCI Insight. 2021. PMID: 33830083 Free PMC article.

4

Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice.

Chen J, Wang R, Xiong F, Sun H, Kemper B, Li W, Kemper J. Chen J, et al. Elife. 2024 Apr 15;13:RP91438. doi: 10.7554/eLife.91438. Elife. 2024. PMID: 38619504 Free PMC article.

5

Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.

Bao Y, Wu X, Chen J, Hu X, Zeng F, Cheng J, Jin H, Lin X, Chen LF. Bao Y, et al. Among authors: chen j, chen lf. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3993-E4001. doi: 10.1073/pnas.1700109114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461486 Free PMC article.

6

Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways.

Zhao XL, Chen JJ, Zhang GN, Wang YC, Si SY, Chen LF, Wang Z. Zhao XL, et al. Sci Rep. 2017 Sep 4;7(1):10397. doi: 10.1038/s41598-017-10929-3. Sci Rep. 2017. PMID: 28871136 Free PMC article.

7

Helicobacter pylori activates NF-κB by inducing Ubc13-mediated ubiquitination of lysine 158 of TAK1.

Lamb A, Chen J, Blanke SR, Chen LF. Lamb A, et al. Among authors: chen j, chen lf. J Cell Biochem. 2013 Oct;114(10):2284-92. doi: 10.1002/jcb.24573. J Cell Biochem. 2013. PMID: 23606331 Free PMC article.

8

T63 inhibits osteoclast differentiation through regulating MAPKs and Akt signaling pathways.

Zhao XL, Chen JJ, Si SY, Chen LF, Wang Z. Zhao XL, et al. Eur J Pharmacol. 2018 Sep 5;834:30-35. doi: 10.1016/j.ejphar.2018.07.009. Epub 2018 Jul 19. Eur J Pharmacol. 2018. PMID: 30012501

9

BET Inhibition Attenuates Helicobacter pylori-Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation.

Chen J, Wang Z, Hu X, Chen R, Romero-Gallo J, Peek RM Jr, Chen LF. Chen J, et al. Among authors: chen r, chen lf. J Immunol. 2016 May 15;196(10):4132-42. doi: 10.4049/jimmunol.1502261. Epub 2016 Apr 15. J Immunol. 2016. PMID: 27084101 Free PMC article.

10

LncRNA SERPINB9P1 Mitigates Cerebral Injury Induced by Oxygen‒Glucose Deprivation/Reoxygenation by Interacting with HSPA2.

Lv M, Song X, Wang W, Li J, Chen J, Huang X, Su L, Gu L. Lv M, et al. Among authors: chen j. Mol Neurobiol. 2025 Jan 11. doi: 10.1007/s12035-024-04646-y. Online ahead of print. Mol Neurobiol. 2025. PMID: 39798045

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