Alt FW - Search Results

1

Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing.

Paulsen BS, Mandal PK, Frock RL, Boyraz B, Yadav R, Upadhyayula S, Gutierrez-Martinez P, Ebina W, Fasth A, Kirchhausen T, Talkowski ME, Agarwal S, Alt FW, Rossi DJ. Paulsen BS, et al. Among authors: alt fw. Nat Biomed Eng. 2017 Nov;1(11):878-888. doi: 10.1038/s41551-017-0145-2. Epub 2017 Oct 9. Nat Biomed Eng. 2017. PMID: 31015609 Free PMC article.

2

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.

Frank KM, Sekiguchi JM, Seidl KJ, Swat W, Rathbun GA, Cheng HL, Davidson L, Kangaloo L, Alt FW. Frank KM, et al. Among authors: alt fw. Nature. 1998 Nov 12;396(6707):173-7. doi: 10.1038/24172. Nature. 1998. PMID: 9823897

3

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development.

Gao Y, Ferguson DO, Xie W, Manis JP, Sekiguchi J, Frank KM, Chaudhuri J, Horner J, DePinho RA, Alt FW. Gao Y, et al. Among authors: alt fw. Nature. 2000 Apr 20;404(6780):897-900. doi: 10.1038/35009138. Nature. 2000. PMID: 10786799

4

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

Bassing CH, Alt FW, Hughes MM, D'Auteuil M, Wehrly TD, Woodman BB, Gärtner F, White JM, Davidson L, Sleckman BP. Bassing CH, et al. Among authors: alt fw. Nature. 2000 Jun 1;405(6786):583-6. doi: 10.1038/35014635. Nature. 2000. PMID: 10850719

5

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells.

Solymar DC, Agarwal S, Bassing CH, Alt FW, Rao A. Solymar DC, et al. Among authors: alt fw. Immunity. 2002 Jul;17(1):41-50. doi: 10.1016/s1074-7613(02)00334-5. Immunity. 2002. PMID: 12150890 Free article.

6

Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity.

Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Ansel KM, et al. Among authors: alt fw. Nat Immunol. 2004 Dec;5(12):1251-9. doi: 10.1038/ni1135. Epub 2004 Oct 31. Nat Immunol. 2004. PMID: 15516924

7

IgH class switching and translocations use a robust non-classical end-joining pathway.

Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW. Yan CT, et al. Among authors: alt fw. Nature. 2007 Sep 27;449(7161):478-82. doi: 10.1038/nature06020. Epub 2007 Aug 22. Nature. 2007. PMID: 17713479

8

Mechanisms promoting translocations in editing and switching peripheral B cells.

Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW. Wang JH, et al. Among authors: alt fw. Nature. 2009 Jul 9;460(7252):231-6. doi: 10.1038/nature08159. Nature. 2009. PMID: 19587764 Free PMC article.

9

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW. Zha S, et al. Among authors: alt fw. Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15. Nature. 2011. PMID: 21160472 Free PMC article.

10

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.

Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, Myers DR, Choi VW, Compagno M, Malkin DJ, Neuberg D, Monti S, Giallourakis CC, Gostissa M, Alt FW. Chiarle R, et al. Among authors: alt fw. Cell. 2011 Sep 30;147(1):107-19. doi: 10.1016/j.cell.2011.07.049. Cell. 2011. PMID: 21962511 Free PMC article.

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