Frock RL - Search Results

1

Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing.

Paulsen BS, Mandal PK, Frock RL, Boyraz B, Yadav R, Upadhyayula S, Gutierrez-Martinez P, Ebina W, Fasth A, Kirchhausen T, Talkowski ME, Agarwal S, Alt FW, Rossi DJ. Paulsen BS, et al. Among authors: frock rl. Nat Biomed Eng. 2017 Nov;1(11):878-888. doi: 10.1038/s41551-017-0145-2. Epub 2017 Oct 9. Nat Biomed Eng. 2017. PMID: 31015609 Free PMC article.

2

Increased AID Results in Mutations at the CRLF2 Locus Implicated in Latin American ALL Health Disparities.

Pannunzio N, Rangel V, Sterrenberg J, Garawi A, Mezcord V, Folkerts M, Caulderon S, Wang J, Soyfer E, Eng O, Valerin J, Tanjasiri S, Quintero-Rivera F, Masri S, Seldin M, Frock R, Fleischman A. Pannunzio N, et al. Res Sq [Preprint]. 2023 Sep 11:rs.3.rs-3332673. doi: 10.21203/rs.3.rs-3332673/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Jul 27;15(1):6331. doi: 10.1038/s41467-024-50537-0 PMID: 37790327 Free PMC article. Updated. Preprint.

3

Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation.

Wang J, Le Gall J, Frock RL, Strick TR. Wang J, et al. Among authors: frock rl. Nat Struct Mol Biol. 2023 Nov;30(11):1707-1718. doi: 10.1038/s41594-023-01104-6. Epub 2023 Oct 12. Nat Struct Mol Biol. 2023. PMID: 37828409 Free PMC article.

4

Author Correction: Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation.

Wang J, Le Gall J, Frock RL, Strick TR. Wang J, et al. Among authors: frock rl. Nat Struct Mol Biol. 2024 Mar;31(3):578. doi: 10.1038/s41594-024-01247-0. Nat Struct Mol Biol. 2024. PMID: 38443719 Free PMC article. No abstract available.

5

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.

Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, Myers DR, Choi VW, Compagno M, Malkin DJ, Neuberg D, Monti S, Giallourakis CC, Gostissa M, Alt FW. Chiarle R, et al. Among authors: frock rl. Cell. 2011 Sep 30;147(1):107-19. doi: 10.1016/j.cell.2011.07.049. Cell. 2011. PMID: 21962511 Free PMC article.

6

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

Frock RL, Hu J, Meyers RM, Ho YJ, Kii E, Alt FW. Frock RL, et al. Nat Biotechnol. 2015 Feb;33(2):179-86. doi: 10.1038/nbt.3101. Epub 2014 Dec 15. Nat Biotechnol. 2015. PMID: 25503383 Free PMC article.

7

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.

Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW. Hu J, et al. Among authors: frock rl. Cell. 2015 Nov 5;163(4):947-59. doi: 10.1016/j.cell.2015.10.016. Epub 2015 Oct 22. Cell. 2015. PMID: 26593423 Free PMC article.

8

Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing.

Hu J, Meyers RM, Dong J, Panchakshari RA, Alt FW, Frock RL. Hu J, et al. Among authors: frock rl. Nat Protoc. 2016 May;11(5):853-71. doi: 10.1038/nprot.2016.043. Epub 2016 Mar 31. Nat Protoc. 2016. PMID: 27031497 Free PMC article.

9

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development.

Zhao L, Frock RL, Du Z, Hu J, Chen L, Krangel MS, Alt FW. Zhao L, et al. Among authors: frock rl. J Exp Med. 2016 Aug 22;213(9):1921-36. doi: 10.1084/jem.20160670. Epub 2016 Aug 15. J Exp Med. 2016. PMID: 27526713 Free PMC article.

10

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.

Kumar V, Alt FW, Frock RL. Kumar V, et al. Among authors: frock rl. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10619-24. doi: 10.1073/pnas.1611882113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601633 Free PMC article.

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