Yang X - Search Results

1

Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension.

Wang Z, Jiang X, Zhang X, Tian G, Yang R, Wu J, Zou X, Liu Z, Yang X, Wu C, Shi J, Li J, Suo J, Wang Y, Zhang R, Xu Z, Gong X, He Y, Zhu W, Aisa HA, Jiang H, Xu Y, Shen J. Wang Z, et al. Among authors: yang r, yang x. J Med Chem. 2019 May 23;62(10):4979-4990. doi: 10.1021/acs.jmedchem.9b00123. Epub 2019 May 8. J Med Chem. 2019. PMID: 31021628

2

Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.

Wang G, Liu Z, Chen T, Wang Z, Yang H, Zheng M, Ren J, Tian G, Yang X, Li L, Li J, Suo J, Zhang R, Jiang X, Terrett NK, Shen J, Xu Y, Jiang H. Wang G, et al. Among authors: yang h, yang x. J Med Chem. 2012 Dec 13;55(23):10540-50. doi: 10.1021/jm301159y. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23137303

3

Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.

Gong X, Wang G, Ren J, Liu Z, Wang Z, Chen T, Yang X, Jiang X, Shen J, Jiang H, Aisa HA, Xu Y, Li J. Gong X, et al. Among authors: yang x. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4944-7. doi: 10.1016/j.bmcl.2013.06.062. Epub 2013 Jun 29. Bioorg Med Chem Lett. 2013. PMID: 23867165

4

Design, synthesis and biological evaluation of 2,5-dimethylfuran-3-carboxylic acid derivatives as potential IDO1 inhibitors.

Yang X, Cai S, Liu X, Chen P, Zhou J, Zhang H. Yang X, et al. Bioorg Med Chem. 2019 Apr 15;27(8):1605-1618. doi: 10.1016/j.bmc.2019.03.005. Epub 2019 Mar 5. Bioorg Med Chem. 2019. PMID: 30858027

5

Design, synthesis and biological evaluation of bicyclic carboxylic acid derivatives as IDO1 inhibitors.

Cai S, Yang X, Chen P, Liu X, Zhou J, Zhang H. Cai S, et al. Among authors: yang x. Bioorg Chem. 2020 Jan;94:103356. doi: 10.1016/j.bioorg.2019.103356. Epub 2019 Nov 21. Bioorg Chem. 2020. PMID: 31785855

6

Design and application of anthracene derivative with aggregation-induced emission charateristics for visualization and monitoring of erythropoietin unfolding.

Sun B, Yang X, Ma L, Niu C, Wang F, Na N, Wen J, Ouyang J. Sun B, et al. Among authors: yang x. Langmuir. 2013 Feb 12;29(6):1956-62. doi: 10.1021/la3048278. Epub 2013 Jan 30. Langmuir. 2013. PMID: 23323829

7

A simple cellulose acetate membrane-based small lanes technique for protein electrophoresis.

Na N, Liu T, Yang X, Sun B, Ouyang J, Ouyang J. Na N, et al. Among authors: yang x. Anal Bioanal Chem. 2012 Aug;404(3):753-62. doi: 10.1007/s00216-012-6168-3. Epub 2012 Jul 1. Anal Bioanal Chem. 2012. PMID: 22752445

8

A near-infrared fluorescent probe based on boric acid hydrolysis for hydrogen peroxide detection and imaging in HeLa cells.

Wang T, Yang X, Men J, Zhou J, Zhang H. Wang T, et al. Among authors: yang x. Luminescence. 2020 Mar;35(2):208-214. doi: 10.1002/bio.3715. Epub 2019 Nov 24. Luminescence. 2020. PMID: 31760681

9

The CH3CH2N: diradical: generation conditions and determination of its ionization energies.

Yang X, Sun Z, Ge M, Zheng S, Meng L, Wang D. Yang X, et al. Chemphyschem. 2002 Nov 15;3(11):963-6. doi: 10.1002/1439-7641(20021115)3:11<963::AID-CPHC963>3.0.CO;2-Q. Chemphyschem. 2002. PMID: 12503138 No abstract available.

10

A Near-infrared Fluorescent Probe of Dicyanoisophorone Derivatives for Selective Detection and Fluorescence Cellular Imaging of Palladium.

Wu H, Yang X, Men J, Zhang H, Zhou J. Wu H, et al. Among authors: yang x. Anal Sci. 2019 Dec 10;35(12):1305-1310. doi: 10.2116/analsci.19P136. Epub 2019 Jul 12. Anal Sci. 2019. PMID: 31308296 Free article.

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