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Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma.
Ikemori R, Gabasa M, Duch P, Vizoso M, Bragado P, Arshakyan M, Luis IC, Marín A, Morán S, Castro M, Fuster G, Gea-Sorli S, Jauset T, Soucek L, Montuenga LM, Esteller M, Monsó E, Peinado VI, Gascon P, Fillat C, Hilberg F, Reguart N, Alcaraz J. Ikemori R, et al. Among authors: alcaraz j. Cancer Res. 2020 Jan 15;80(2):276-290. doi: 10.1158/0008-5472.CAN-19-0637. Epub 2019 Nov 6. Cancer Res. 2020. PMID: 31694906
MMP1 drives tumor progression in large cell carcinoma of the lung through fibroblast senescence.
Gabasa M, Radisky ES, Ikemori R, Bertolini G, Arshakyan M, Hockla A, Duch P, Rondinone O, Llorente A, Maqueda M, Davalos A, Gavilán E, Perera A, Ramírez J, Gascón P, Reguart N, Roz L, Radisky DC, Alcaraz J. Gabasa M, et al. Among authors: alcaraz j. Cancer Lett. 2021 Jun 1;507:1-12. doi: 10.1016/j.canlet.2021.01.028. Epub 2021 Mar 6. Cancer Lett. 2021. PMID: 33684534 Free PMC article.
Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma.
Duch P, Díaz-Valdivia N, Ikemori R, Gabasa M, Radisky ES, Arshakyan M, Gea-Sorlí S, Mateu-Bosch A, Bragado P, Carrasco JL, Mori H, Ramírez J, Teixidó C, Reguart N, Fillat C, Radisky DC, Alcaraz J. Duch P, et al. Among authors: alcaraz j. Matrix Biol. 2022 Aug;111:207-225. doi: 10.1016/j.matbio.2022.06.009. Epub 2022 Jul 2. Matrix Biol. 2022. PMID: 35787446 Free PMC article.
Aberrant TIMP-1 production in tumor-associated fibroblasts drives the selective benefits of nintedanib in lung adenocarcinoma.
Duch P, Díaz-Valdivia N, Gabasa M, Ikemori R, Arshakyan M, Fernández-Nogueira P, Llorente A, Teixido C, Ramírez J, Pereda J, Chuliá-Peris L, Galbis JM, Hilberg F, Reguart N, Radisky DC, Alcaraz J. Duch P, et al. Among authors: alcaraz j. Cancer Sci. 2024 May;115(5):1505-1519. doi: 10.1111/cas.16141. Epub 2024 Mar 12. Cancer Sci. 2024. PMID: 38476010 Free PMC article.
173 results