Ildefonso CJ - Search Results

1

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors.

Brown EE, DeWeerd AJ, Ildefonso CJ, Lewin AS, Ash JD. Brown EE, et al. Among authors: ildefonso cj. Redox Biol. 2019 Jun;24:101201. doi: 10.1016/j.redox.2019.101201. Epub 2019 Apr 20. Redox Biol. 2019. PMID: 31039480 Free PMC article.

2

Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation.

Ildefonso CJ, Jaime H, Rahman MM, Li Q, Boye SE, Hauswirth WW, Lucas AR, McFadden G, Lewin AS. Ildefonso CJ, et al. Hum Gene Ther. 2015 Jan;26(1):59-68. doi: 10.1089/hum.2014.089. Hum Gene Ther. 2015. PMID: 25420215 Free PMC article.

3

Gene therapy with the caspase activation and recruitment domain reduces the ocular inflammatory response.

Ildefonso CJ, Jaime H, Biswal MR, Boye SE, Li Q, Hauswirth WW, Lewin AS. Ildefonso CJ, et al. Mol Ther. 2015 May;23(5):875-884. doi: 10.1038/mt.2015.30. Epub 2015 Feb 20. Mol Ther. 2015. PMID: 25698151 Free PMC article.

4

Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress.

Biswal MR, Ahmed CM, Ildefonso CJ, Han P, Li H, Jivanji H, Mao H, Lewin AS. Biswal MR, et al. Among authors: ildefonso cj. Exp Eye Res. 2015 Nov;140:94-105. doi: 10.1016/j.exer.2015.07.022. Epub 2015 Aug 25. Exp Eye Res. 2015. PMID: 26315784 Free PMC article.

5

Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration.

Biswal MR, Ildefonso CJ, Mao H, Seo SJ, Wang Z, Li H, Le YZ, Lewin AS. Biswal MR, et al. Among authors: ildefonso cj. Adv Exp Med Biol. 2016;854:31-7. doi: 10.1007/978-3-319-17121-0_5. Adv Exp Med Biol. 2016. PMID: 26427390

6

The NLRP3 Inflammasome and its Role in Age-Related Macular Degeneration.

Ildefonso CJ, Biswal MR, Ahmed CM, Lewin AS. Ildefonso CJ, et al. Adv Exp Med Biol. 2016;854:59-65. doi: 10.1007/978-3-319-17121-0_9. Adv Exp Med Biol. 2016. PMID: 26427394 Review.

7

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide.

Ildefonso CJ, Jaime H, Brown EE, Iwata RL, Ahmed CM, Massengill MT, Biswal MR, Boye SE, Hauswirth WW, Ash JD, Li Q, Lewin AS. Ildefonso CJ, et al. Invest Ophthalmol Vis Sci. 2016 Feb;57(2):372-86. doi: 10.1167/iovs.15-17703. Invest Ophthalmol Vis Sci. 2016. PMID: 26842755 Free PMC article.

8

Repurposing an orally available drug for the treatment of geographic atrophy.

Ahmed CM, Biswal MR, Li H, Han P, Ildefonso CJ, Lewin AS. Ahmed CM, et al. Among authors: ildefonso cj. Mol Vis. 2016 Apr 2;22:294-310. eCollection 2016. Mol Vis. 2016. PMID: 27110092 Free PMC article.

9

Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.

Biswal MR, Han P, Zhu P, Wang Z, Li H, Ildefonso CJ, Lewin AS. Biswal MR, et al. Among authors: ildefonso cj. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1237-1245. doi: 10.1167/iovs.16-21272. Invest Ophthalmol Vis Sci. 2017. PMID: 28241311 Free PMC article.

10

Neuroinflammation in Retinitis Pigmentosa, Diabetic Retinopathy, and Age-Related Macular Degeneration: A Minireview.

Massengill MT, Ahmed CM, Lewin AS, Ildefonso CJ. Massengill MT, et al. Among authors: ildefonso cj. Adv Exp Med Biol. 2018;1074:185-191. doi: 10.1007/978-3-319-75402-4_23. Adv Exp Med Biol. 2018. PMID: 29721943 Review.

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