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73 results

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Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults.
Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS Jr, Nafziger AN, Ma JD. Yang J, et al. Among authors: greenberg he. J Clin Pharmacol. 2019 Nov;59(11):1495-1504. doi: 10.1002/jcph.1440. Epub 2019 May 3. J Clin Pharmacol. 2019. PMID: 31051051
Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach.
Yang J, Patel M, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Aubrey Stoch S, Bertino JS Jr, Nafziger AN, Ma JD. Yang J, et al. Among authors: greenberg he. J Clin Pharmacol. 2018 Sep;58(9):1205-1213. doi: 10.1002/jcph.1125. Epub 2018 Apr 17. J Clin Pharmacol. 2018. PMID: 29663428
Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and without aprepitant.
Stoch SA, Gargano C, Valentine J, Braun MP, Murphy MG, Fedgchin M, Majumdar A, Pequignot E, Gottesdiener KM, Petty KJ, Panebianco D, Dean D, Kraft WK, Greenberg HE. Stoch SA, et al. Among authors: greenberg he. Cancer Chemother Pharmacol. 2011 Jun;67(6):1313-21. doi: 10.1007/s00280-010-1421-y. Epub 2010 Aug 24. Cancer Chemother Pharmacol. 2011. PMID: 20734049 Clinical Trial.
The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.
Agrawal NG, Matthews CZ, Mazenko RS, Woolf EJ, Porras AG, Chen X, Miller JL, Michiels N, Wehling M, Schultz A, Gottlieb AB, Kraft WK, Greenberg HE, Waldman SA, Curtis SP, Gottesdiener KM. Agrawal NG, et al. Among authors: greenberg he. J Clin Pharmacol. 2004 Oct;44(10):1125-31. doi: 10.1177/0091270004268129. J Clin Pharmacol. 2004. PMID: 15342613 Clinical Trial.
Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers.
Majumdar AK, Howard L, Goldberg MR, Hickey L, Constanzer M, Rothenberg PL, Crumley TM, Panebianco D, Bradstreet TE, Bergman AJ, Waldman SA, Greenberg HE, Butler K, Knops A, De Lepeleire I, Michiels N, Petty KJ. Majumdar AK, et al. Among authors: greenberg he. J Clin Pharmacol. 2006 Mar;46(3):291-300. doi: 10.1177/0091270005283467. J Clin Pharmacol. 2006. PMID: 16490805 Clinical Trial.
Effect of aprepitant on the pharmacokinetics of intravenous midazolam.
Majumdar AK, Yan KX, Selverian DV, Barlas S, Constanzer M, Dru J, McCrea JB, Ahmed T, Frick GS, Kraft WK, Petty KJ, Greenberg HE. Majumdar AK, et al. Among authors: greenberg he. J Clin Pharmacol. 2007 Jun;47(6):744-50. doi: 10.1177/0091270007300807. Epub 2007 Apr 26. J Clin Pharmacol. 2007. PMID: 17463213 Clinical Trial.
73 results