Ferraris DM - Search Results

1

Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.

Singh V, Pacitto A, Donini S, Ferraris DM, Boros S, Illyés E, Szokol B, Rizzi M, Blundell TL, Ascher DB, Pato J, Mizrahi V. Singh V, et al. Among authors: ferraris dm. Eur J Med Chem. 2019 Jul 15;174:309-329. doi: 10.1016/j.ejmech.2019.04.027. Epub 2019 Apr 15. Eur J Med Chem. 2019. PMID: 31055147 Free PMC article.

2

Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity.

Ferraris DM, Sbardella D, Petrera A, Marini S, Amstutz B, Coletta M, Sander P, Rizzi M. Ferraris DM, et al. J Biol Chem. 2011 Sep 16;286(37):32475-82. doi: 10.1074/jbc.M111.271809. Epub 2011 Aug 3. J Biol Chem. 2011. PMID: 21813647 Free PMC article.

3

Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3.

Ferraris DM, Spallek R, Oehlmann W, Singh M, Rizzi M. Ferraris DM, et al. Proteins. 2014 Sep;82(9):2268-74. doi: 10.1002/prot.24548. Epub 2014 Mar 24. Proteins. 2014. PMID: 24615888

4

Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor.

Mori M, Moraca F, Deodato D, Ferraris DM, Selchow P, Sander P, Rizzi M, Botta M. Mori M, et al. Among authors: ferraris dm. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2508-11. doi: 10.1016/j.bmcl.2014.04.004. Epub 2014 Apr 13. Bioorg Med Chem Lett. 2014. PMID: 24767848

5

Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis.

Ferraris DM, Spallek R, Oehlmann W, Singh M, Rizzi M. Ferraris DM, et al. Proteins. 2015 Feb;83(2):389-94. doi: 10.1002/prot.24743. Epub 2015 Jan 7. Proteins. 2015. PMID: 25524525

6

Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.

Donini S, Garavaglia S, Ferraris DM, Miggiano R, Mori S, Shibayama K, Rizzi M. Donini S, et al. Among authors: ferraris dm. PLoS One. 2017 Apr 18;12(4):e0175815. doi: 10.1371/journal.pone.0175815. eCollection 2017. PLoS One. 2017. PMID: 28419153 Free PMC article.

7

Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.

Donini S, Ferraris DM, Miggiano R, Massarotti A, Rizzi M. Donini S, et al. Among authors: ferraris dm. Sci Rep. 2017 Apr 26;7(1):1180. doi: 10.1038/s41598-017-01057-z. Sci Rep. 2017. PMID: 28446777 Free PMC article.

8

Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets.

Ferraris DM, Miggiano R, Rossi F, Rizzi M. Ferraris DM, et al. Pathogens. 2018 Feb 1;7(1):17. doi: 10.3390/pathogens7010017. Pathogens. 2018. PMID: 29389854 Free PMC article. Review.

9

Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1.

Mori M, Deodato D, Kasula M, Ferraris DM, Sanna A, De Logu A, Rizzi M, Botta M. Mori M, et al. Among authors: ferraris dm. Bioorg Med Chem Lett. 2018 Feb 15;28(4):637-641. doi: 10.1016/j.bmcl.2018.01.031. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29395975

10

Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors.

Sahu NU, Singh V, Ferraris DM, Rizzi M, Kharkar PS. Sahu NU, et al. Among authors: ferraris dm. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1714-1718. doi: 10.1016/j.bmcl.2018.04.045. Epub 2018 Apr 18. Bioorg Med Chem Lett. 2018. PMID: 29699922

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