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In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.
J Mol Cell Biol. 2020 Aug 1;12(8):644-653. doi: 10.1093/jmcb/mjz029.
J Mol Cell Biol. 2020.
PMID: 31065693
Free PMC article.
Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.
Leonhard WN, Kunnen SJ, Plugge AJ, Pasternack A, Jianu SB, Veraar K, El Bouazzaoui F, Hoogaars WM, Ten Dijke P, Breuning MH, De Heer E, Ritvos O, Peters DJ.
Leonhard WN, et al. Among authors: plugge aj.
J Am Soc Nephrol. 2016 Dec;27(12):3589-3599. doi: 10.1681/ASN.2015030287. Epub 2016 Mar 28.
J Am Soc Nephrol. 2016.
PMID: 27020852
Free PMC article.
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