Eklund KK - Search Results

1

Forskolin attenuates the NLRP3 inflammasome activation and IL-1β secretion in human macrophages.

Chen Y, Wen JG, Feng JJ, Wang YH, Li TF, Nurmi K, Eklund KK, Xing D. Chen Y, et al. Among authors: eklund kk. Pediatr Res. 2019 Dec;86(6):692-698. doi: 10.1038/s41390-019-0418-4. Epub 2019 May 13. Pediatr Res. 2019. PMID: 31086288

2

Chemically modified tetracyclines induce apoptosis in cultured mast cells.

Sandler C, Nurmi K, Lindstedt KA, Sorsa T, Golub LM, Kovanen PT, Eklund KK. Sandler C, et al. Among authors: eklund kk. Int Immunopharmacol. 2005 Oct;5(11):1611-21. doi: 10.1016/j.intimp.2005.04.013. Int Immunopharmacol. 2005. PMID: 16039551

3

Selective activation of mast cells in rheumatoid synovial tissue results in production of TNF-alpha, IL-1beta and IL-1Ra.

Sandler C, Lindstedt KA, Joutsiniemi S, Lappalainen J, Juutilainen T, Kolah J, Kovanen PT, Eklund KK. Sandler C, et al. Among authors: eklund kk. Inflamm Res. 2007 Jun;56(6):230-9. doi: 10.1007/s00011-007-6135-1. Inflamm Res. 2007. PMID: 17607547

4

Ethanol induces apoptosis in human mast cells.

Nurmi K, Methuen T, Mäki T, Lindstedt KA, Kovanen PT, Sandler C, Eklund KK. Nurmi K, et al. Among authors: eklund kk. Life Sci. 2009 Nov 4;85(19-20):678-84. doi: 10.1016/j.lfs.2009.09.004. Epub 2009 Sep 20. Life Sci. 2009. PMID: 19775596

5

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation.

Rajamäki K, Lappalainen J, Oörni K, Välimäki E, Matikainen S, Kovanen PT, Eklund KK. Rajamäki K, et al. Among authors: eklund kk. PLoS One. 2010 Jul 23;5(7):e11765. doi: 10.1371/journal.pone.0011765. PLoS One. 2010. PMID: 20668705 Free PMC article.

6

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK. Niemi K, et al. Among authors: eklund kk. J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20. J Immunol. 2011. PMID: 21508263

7

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.

Rajamäki K, Nordström T, Nurmi K, Åkerman KE, Kovanen PT, Öörni K, Eklund KK. Rajamäki K, et al. Among authors: eklund kk. J Biol Chem. 2013 May 10;288(19):13410-9. doi: 10.1074/jbc.M112.426254. Epub 2013 Mar 25. J Biol Chem. 2013. PMID: 23530046 Free PMC article.

8

Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-inflammatory action of alcohol.

Nurmi K, Virkanen J, Rajamäki K, Niemi K, Kovanen PT, Eklund KK. Nurmi K, et al. Among authors: eklund kk. PLoS One. 2013 Nov 11;8(11):e78537. doi: 10.1371/journal.pone.0078537. eCollection 2013. PLoS One. 2013. PMID: 24244322 Free PMC article.

9

p38δ MAPK: A Novel Regulator of NLRP3 Inflammasome Activation With Increased Expression in Coronary Atherogenesis.

Rajamäki K, Mäyränpää MI, Risco A, Tuimala J, Nurmi K, Cuenda A, Eklund KK, Öörni K, Kovanen PT. Rajamäki K, et al. Among authors: eklund kk. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1937-46. doi: 10.1161/ATVBAHA.115.307312. Epub 2016 Jul 14. Arterioscler Thromb Vasc Biol. 2016. PMID: 27417584

10

Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.

Välimäki E, Cypryk W, Virkanen J, Nurmi K, Turunen PM, Eklund KK, Åkerman KE, Nyman TA, Matikainen S. Välimäki E, et al. Among authors: eklund kk. J Immunol. 2016 Oct 15;197(8):3315-3325. doi: 10.4049/jimmunol.1501840. Epub 2016 Sep 16. J Immunol. 2016. PMID: 27638862

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