Edginton A - Search Results

1

Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants.

Gerhart JG, Watt KM, Edginton A, Wade KC, Salerno SN, Benjamin DK Jr, Smith PB, Hornik CP, Cohen-Wolkowiez M, Duara S, Ross A, Shattuck K, Stewart DL, Neu N, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: edginton a. CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):500-510. doi: 10.1002/psp4.12414. Epub 2019 May 22. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31087536 Free PMC article.

2

Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform.

Chelle P, Hajducek D, Thibaudeau K, Hobson N, Iorio A, Shapiro A, Edginton A. Chelle P, et al. Among authors: edginton a. Haemophilia. 2024 Jul;30(4):988-997. doi: 10.1111/hae.15027. Epub 2024 May 2. Haemophilia. 2024. PMID: 38698539

3

Integrated Electrochemical Aptamer Biosensing and Colorimetric pH Monitoring via Hydrogel Microneedle Assays for Assessing Antibiotic Treatment.

Keyvani F, GhavamiNejad P, Saleh MA, Soltani M, Zhao Y, Sadeghzadeh S, Shakeri A, Chelle P, Zheng H, Rahman FA, Mahshid S, Quadrilatero J, Rao PPN, Edginton A, Poudineh M. Keyvani F, et al. Among authors: edginton a. Adv Sci (Weinh). 2024 Nov;11(41):e2309027. doi: 10.1002/advs.202309027. Epub 2024 Sep 9. Adv Sci (Weinh). 2024. PMID: 39250329 Free PMC article.

4

Simulation of differential drug pharmacokinetics under heat and exercise stress using a physiologically based pharmacokinetic modeling approach.

Sidhu P, Peng HT, Cheung B, Edginton A. Sidhu P, et al. Among authors: edginton a. Can J Physiol Pharmacol. 2011 May;89(5):365-82. doi: 10.1139/y11-030. Epub 2011 May 31. Can J Physiol Pharmacol. 2011. PMID: 21627485

5

Physiologically based pharmacokinetic modeling and simulation in pediatric drug development.

Maharaj AR, Edginton AN. Maharaj AR, et al. Among authors: edginton an. CPT Pharmacometrics Syst Pharmacol. 2014 Oct 22;3(11):e150. doi: 10.1038/psp.2014.45. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25353188 Free PMC article.

6

Predicting neonatal pharmacokinetics from prior data using population pharmacokinetic modeling.

Wang J, Edginton AN, Avant D, Burckart GJ. Wang J, et al. J Clin Pharmacol. 2015 Oct;55(10):1175-83. doi: 10.1002/jcph.524. Epub 2015 Jun 9. J Clin Pharmacol. 2015. PMID: 25907280

7

Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data.

Hornik CP, Wu H, Edginton AN, Watt K, Cohen-Wolkowiez M, Gonzalez D. Hornik CP, et al. Clin Pharmacokinet. 2017 Nov;56(11):1343-1353. doi: 10.1007/s40262-017-0525-5. Clin Pharmacokinet. 2017. PMID: 28290120 Free PMC article.

8

Improving Pediatric Protein Binding Estimates: An Evaluation of α1-Acid Glycoprotein Maturation in Healthy and Infected Subjects.

Maharaj AR, Gonzalez D, Cohen-Wolkowiez M, Hornik CP, Edginton AN. Maharaj AR, et al. Clin Pharmacokinet. 2018 May;57(5):577-589. doi: 10.1007/s40262-017-0576-7. Clin Pharmacokinet. 2018. PMID: 28779462 Free PMC article.

9

Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid.

Salerno SN, Edginton A, Cohen-Wolkowiez M, Hornik CP, Watt KM, Jamieson BD, Gonzalez D. Salerno SN, et al. Among authors: edginton a. CPT Pharmacometrics Syst Pharmacol. 2017 Dec;6(12):814-822. doi: 10.1002/psp4.12252. Epub 2017 Oct 25. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 29068158 Free PMC article.

10

Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO.

Watt KM, Cohen-Wolkowiez M, Barrett JS, Sevestre M, Zhao P, Brouwer KLR, Edginton AN. Watt KM, et al. CPT Pharmacometrics Syst Pharmacol. 2018 Oct;7(10):629-637. doi: 10.1002/psp4.12338. Epub 2018 Aug 13. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30033691 Free PMC article.

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