Kushnir S - Search Results

1

Identification of crucial bottlenecks in engineered polyketide biosynthesis.

Grote M, Kushnir S, Pryk N, Möller D, Erver J, Ismail-Ali A, Schulz F. Grote M, et al. Among authors: kushnir s. Org Biomol Chem. 2019 Jul 14;17(26):6374-6385. doi: 10.1039/c9ob00831d. Epub 2019 May 15. Org Biomol Chem. 2019. PMID: 31090778

2

Biosynthesis-driven structure-activity relationship study of premonensin-derivatives.

Ismail-Ali A, Fansa EK, Pryk N, Yahiaoui S, Kushnir S, Pflieger M, Wittinghofer A, Schulz F. Ismail-Ali A, et al. Among authors: kushnir s. Org Biomol Chem. 2016 Aug 10;14(32):7671-5. doi: 10.1039/c6ob01201a. Org Biomol Chem. 2016. PMID: 27452503

3

Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway.

Möller D, Kushnir S, Grote M, Ismail-Ali A, Koopmans KRM, Calo F, Heinrich S, Diehl B, Schulz F. Möller D, et al. Among authors: kushnir s. Lett Appl Microbiol. 2018 Sep;67(3):226-234. doi: 10.1111/lam.13039. Epub 2018 Jul 18. Lett Appl Microbiol. 2018. PMID: 29927502

4

Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis.

Bravo-Rodriguez K, Klopries S, Koopmans KRM, Sundermann U, Yahiaoui S, Arens J, Kushnir S, Schulz F, Sanchez-Garcia E. Bravo-Rodriguez K, et al. Among authors: kushnir s. Chem Biol. 2015 Nov 19;22(11):1425-1430. doi: 10.1016/j.chembiol.2015.02.008. Epub 2015 Oct 29. Chem Biol. 2015. PMID: 26526102

5

Minimally invasive mutagenesis gives rise to a biosynthetic polyketide library.

Kushnir S, Sundermann U, Yahiaoui S, Brockmeyer A, Janning P, Schulz F. Kushnir S, et al. Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10664-9. doi: 10.1002/anie.201202438. Epub 2012 Sep 20. Angew Chem Int Ed Engl. 2012. PMID: 22996590

6

Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase.

Sundermann U, Bravo-Rodriguez K, Klopries S, Kushnir S, Gomez H, Sanchez-Garcia E, Schulz F. Sundermann U, et al. Among authors: kushnir s. ACS Chem Biol. 2013 Feb 15;8(2):443-50. doi: 10.1021/cb300505w. Epub 2012 Nov 26. ACS Chem Biol. 2013. PMID: 23181268

7

Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives.

Bravo-Rodriguez K, Ismail-Ali AF, Klopries S, Kushnir S, Ismail S, Fansa EK, Wittinghofer A, Schulz F, Sanchez-Garcia E. Bravo-Rodriguez K, et al. Among authors: kushnir s. Chembiochem. 2014 Sep 5;15(13):1991-7. doi: 10.1002/cbic.201402206. Epub 2014 Jul 15. Chembiochem. 2014. PMID: 25044264

8

Polyether Cyclization Cascade Alterations in Response to Monensin Polyketide Synthase Mutations.

Heinrich S, Grote M, Sievers S, Kushnir S, Schulz F. Heinrich S, et al. Among authors: kushnir s. Chembiochem. 2022 Jan 19;23(2):e202100584. doi: 10.1002/cbic.202100584. Epub 2021 Nov 26. Chembiochem. 2022. PMID: 34729883

9

Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis.

Klopries S, Bravo-Rodriguez K, Koopmans KR, Sundermann U, Yahiaoui S, Arens J, Kushnir S, Sanchez-Garcia E, Schulz F. Klopries S, et al. Among authors: kushnir s. Data Brief. 2015 Oct 14;5:528-36. doi: 10.1016/j.dib.2015.09.052. eCollection 2015 Dec. Data Brief. 2015. PMID: 26587559 Free PMC article.

10

The development of DNA sequencing: from the genome of a bacteriophage to that of a Neanderthal.

Sundermann U, Kushnir S, Schulz F. Sundermann U, et al. Among authors: kushnir s. Angew Chem Int Ed Engl. 2010 Nov 15;49(47):8795-7. doi: 10.1002/anie.201003880. Angew Chem Int Ed Engl. 2010. PMID: 20862760 No abstract available.

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