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Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.
Picco G, Chen ED, Alonso LG, Behan FM, Gonçalves E, Bignell G, Matchan A, Fu B, Banerjee R, Anderson E, Butler A, Benes CH, McDermott U, Dow D, Iorio F, Stronach E, Yang F, Yusa K, Saez-Rodriguez J, Garnett MJ. Picco G, et al. Among authors: chen ed. Nat Commun. 2019 May 16;10(1):2198. doi: 10.1038/s41467-019-09940-1. Nat Commun. 2019. PMID: 31097696 Free PMC article.
Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.
Iorio F, Behan FM, Gonçalves E, Bhosle SG, Chen E, Shepherd R, Beaver C, Ansari R, Pooley R, Wilkinson P, Harper S, Butler AP, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. Iorio F, et al. BMC Genomics. 2018 Aug 13;19(1):604. doi: 10.1186/s12864-018-4989-y. BMC Genomics. 2018. PMID: 30103702 Free PMC article.
GDSCTools for mining pharmacogenomic interactions in cancer.
Cokelaer T, Chen E, Iorio F, Menden MP, Lightfoot H, Saez-Rodriguez J, Garnett MJ. Cokelaer T, et al. Bioinformatics. 2018 Apr 1;34(7):1226-1228. doi: 10.1093/bioinformatics/btx744. Bioinformatics. 2018. PMID: 29186349 Free PMC article.
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP. Balmus G, et al. Nat Commun. 2019 Jan 8;10(1):87. doi: 10.1038/s41467-018-07729-2. Nat Commun. 2019. PMID: 30622252 Free PMC article.
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics.
Li X, Francies HE, Secrier M, Perner J, Miremadi A, Galeano-Dalmau N, Barendt WJ, Letchford L, Leyden GM, Goffin EK, Barthorpe A, Lightfoot H, Chen E, Gilbert J, Noorani A, Devonshire G, Bower L, Grantham A, MacRae S, Grehan N, Wedge DC, Fitzgerald RC, Garnett MJ. Li X, et al. Nat Commun. 2018 Jul 30;9(1):2983. doi: 10.1038/s41467-018-05190-9. Nat Commun. 2018. PMID: 30061675 Free PMC article.
[Amiodarone-induced severve hyponatremia: a case report].
Sheng QH, Chen ED, Zhang L, Hong T. Sheng QH, et al. Among authors: chen ed. Zhonghua Xin Xue Guan Bing Za Zhi. 2024 Oct 24;52(10):1207-1208. doi: 10.3760/cma.j.cn112148-20240824-00476. Zhonghua Xin Xue Guan Bing Za Zhi. 2024. PMID: 39428371 Chinese.
Newtonian gravitation in Maxwell spacetime.
Chen ED. Chen ED. Stud Hist Philos Sci. 2023 Dec;102:22-30. doi: 10.1016/j.shpsa.2023.08.003. Epub 2023 Oct 3. Stud Hist Philos Sci. 2023. PMID: 37797386
34 results