Yim JH - Search Results

1

Combination therapy with BYL719 and LEE011 is synergistic and causes a greater suppression of p-S6 in triple negative breast cancer.

Yuan Y, Wen W, Yost SE, Xing Q, Yan J, Han ES, Mortimer J, Yim JH. Yuan Y, et al. Among authors: yim jh. Sci Rep. 2019 May 17;9(1):7509. doi: 10.1038/s41598-019-43429-7. Sci Rep. 2019. PMID: 31101835 Free PMC article.

2

IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells.

Gao J, Senthil M, Ren B, Yan J, Xing Q, Yu J, Zhang L, Yim JH. Gao J, et al. Among authors: yim jh. Cell Death Differ. 2010 Apr;17(4):699-709. doi: 10.1038/cdd.2009.156. Epub 2009 Oct 23. Cell Death Differ. 2010. PMID: 19851330 Free PMC article.

3

Identification of a natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression.

Gao J, Wang Y, Xing Q, Yan J, Senthil M, Akmal Y, Kowolik CM, Kang J, Lu DM, Zhao M, Lin Z, Cheng CH, Yip ML, Yim JH. Gao J, et al. Among authors: yim jh. Mol Cancer Ther. 2011 Oct;10(10):1774-83. doi: 10.1158/1535-7163.MCT-11-0304. Epub 2011 Aug 4. Mol Cancer Ther. 2011. PMID: 21817116 Free PMC article.

4

Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells.

Armstrong MJ, Stang MT, Liu Y, Gao J, Ren B, Zuckerbraun BS, Mahidhara RS, Xing Q, Pizzoferrato E, Yim JH. Armstrong MJ, et al. Among authors: yim jh. Cancer Lett. 2012 Jun 1;319(1):56-65. doi: 10.1016/j.canlet.2011.12.027. Epub 2011 Dec 23. Cancer Lett. 2012. PMID: 22200613 Free PMC article.

5

Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer.

Wen W, Liang W, Wu J, Kowolik CM, Buettner R, Scuto A, Hsieh MY, Hong H, Brown CE, Forman SJ, Horne D, Morgan R, Wakabayashi M, Dellinger TH, Han ES, Yim JH, Jove R. Wen W, et al. Among authors: yim jh. Mol Cancer Ther. 2014 Dec;13(12):3037-48. doi: 10.1158/1535-7163.MCT-14-0077. Epub 2014 Oct 15. Mol Cancer Ther. 2014. PMID: 25319391 Free PMC article.

6

Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells.

Wang Y, Han E, Xing Q, Yan J, Arrington A, Wang C, Tully D, Kowolik CM, Lu DM, Frankel PH, Zhai J, Wen W, Horne D, Yip MLR, Yim JH. Wang Y, et al. Among authors: yim jh. Cancer Lett. 2015 Mar 28;358(2):170-179. doi: 10.1016/j.canlet.2014.12.033. Epub 2014 Dec 25. Cancer Lett. 2015. PMID: 25543165 Free PMC article.

7

Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer.

Wen W, Wu J, Liu L, Tian Y, Buettner R, Hsieh MY, Horne D, Dellinger TH, Han ES, Jove R, Yim JH. Wen W, et al. Among authors: yim jh. Mol Cancer. 2015 May 1;14:100. doi: 10.1186/s12943-015-0366-5. Mol Cancer. 2015. PMID: 25928246 Free PMC article.

8

IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.

Armstrong MJ, Stang MT, Liu Y, Yan J, Pizzoferrato E, Yim JH. Armstrong MJ, et al. Among authors: yim jh. Cancer Biol Ther. 2015;16(7):1029-41. doi: 10.1080/15384047.2015.1046646. Cancer Biol Ther. 2015. PMID: 26011589 Free PMC article.

9

Characterization of patient-derived tumor xenografts (PDXs) as models for estrogen receptor positive (ER+HER2- and ER+HER2+) breast cancers.

Kanaya N, Somlo G, Wu J, Frankel P, Kai M, Liu X, Wu SV, Nguyen D, Chan N, Hsieh MY, Kirschenbaum M, Kruper L, Vito C, Badie B, Yim JH, Yuan Y, Hurria A, Peiguo C, Mortimer J, Chen S. Kanaya N, et al. Among authors: yim jh. J Steroid Biochem Mol Biol. 2017 Jun;170:65-74. doi: 10.1016/j.jsbmb.2016.05.001. Epub 2016 May 3. J Steroid Biochem Mol Biol. 2017. PMID: 27154416 Free PMC article.

10

Cinnamon extract reduces VEGF expression via suppressing HIF-1α gene expression and inhibits tumor growth in mice.

Zhang K, Han ES, Dellinger TH, Lu J, Nam S, Anderson RA, Yim JH, Wen W. Zhang K, et al. Among authors: yim jh. Mol Carcinog. 2017 Feb;56(2):436-446. doi: 10.1002/mc.22506. Epub 2016 Jun 15. Mol Carcinog. 2017. PMID: 27253180 Free PMC article.

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